Evidence map›Paper›PMID 29997179›Full record

ArticleThe EMBO journal2018

Shelterin promotes tethering of late replication origins to telomeres for replication-timing control.

Shiho Ogawa, Sayuri Kido, Tetsuya Handa, Hidesato Ogawa, Haruhiko Asakawa, Tatsuro S Takahashi, Takuro Nakagawa, Yasushi Hiraoka, Hisao Masukata

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Control of DNA replication timing in the 3D genome.Nature reviews. Molecular cell biology · 2019
    Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shiho OgawaGraduate School of Science, Osaka University, Toyonaka Osaka, Japan.
Sayuri KidoGraduate School of Science, Osaka University, Toyonaka Osaka, Japan.
Tetsuya HandaGraduate School of Science, Osaka University, Toyonaka Osaka, Japan.
Hidesato OgawaGraduate School of Frontier Biosciences, Osaka University, Suita Osaka, Japan.ORCID 0000-0001-9740-9010
Haruhiko AsakawaGraduate School of Frontier Biosciences, Osaka University, Suita Osaka, Japan.
Tatsuro S TakahashiGraduate School of Science, Osaka University, Toyonaka Osaka, Japan.ORCID 0000-0002-1947-7680
Takuro NakagawaGraduate School of Science, Osaka University, Toyonaka Osaka, Japan.ORCID 0000-0003-3455-8224
Yasushi HiraokaGraduate School of Frontier Biosciences, Osaka University, Suita Osaka, Japan.
Hisao MasukataGraduate School of Science, Osaka University, Toyonaka Osaka, Japan masukata@bio.sci.osaka-u.ac.jp.ORCID 0000-0002-4918-3982
The University of Osaka · JPUbe Frontier University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA replication initiates at many discrete loci on eukaryotic chromosomes, and individual replication origins are regulated under a spatiotemporal program. However, the underlying mechanisms of this regulation remain largely unknown. In the fission yeast

Indexed as

DNA-Binding ProteinsDNA ReplicationG1 PhaseMembrane ProteinsNuclear ProteinsRecombinant Fusion ProteinsReplication OriginSchizosaccharomycesSchizosaccharomyces pombe ProteinsShelterin ComplexS PhaseTelomereTelomere-Binding ProteinsTelomeric Repeat Binding Protein 2Bqt4 protein, S pombeDNA-Binding ProteinsMembrane ProteinsNuclear ProteinsPoz1 protein, S pombeRap1 protein, S pombeRecombinant Fusion ProteinsSchizosaccharomyces pombe ProteinsShelterin Complextaz1 protein, S pombeTelomere-Binding ProteinsTelomeric Repeat Binding Protein 2chromatin organizationRap1replication timingTaz1telomere

Identifiers

PMID29997179
PMCPMC6068461
OpenAlexW2868744887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.