Evidence map›Paper›PMID 29997144›Full record

ArticleBMJ open2018

Anticoagulation therapy in patients with stroke and atrial fibrillation: a registry-based study of acute stroke care in Surrey, UK.

Thang S Han, Christopher Henry Fry, David Fluck, Brendan Affley, Giosue Gulli, Christopher Barrett, Puneet Kakar, Tasmin Patel, Sapna Sharma, Pankaj Sharma

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  10. New evidence-based A1, A2, A3 alarm time zones for transferring thrombolysed patients to hyper-acute stroke units: faster is better.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Thang S HanInstitute of Cardiovascular Research, Royal Holloway, University of London, London, UK.ORCID 0000-0003-2570-0938
Christopher Henry FrySchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
David FluckDepartment of Cardiology, Ashford and St Peter's NHS Foundation Trust, Chertsey, UK.
Brendan AffleyDepartment of Stroke, Ashford and Saint Peter's Hospitals NHS Trust, Chertsey, UK.
Giosue GulliDepartment of Stroke, Ashford and Saint Peter's Hospitals NHS Trust, Chertsey, UK.
Christopher BarrettDepartment of Stroke, NHS Frimley Health Foundation Trust, Frimley, UK.
Puneet KakarDepartment of Stroke, Epsom and St Helier University Hospitals, Epsom, UK.
Tasmin PatelInstitute of Cardiovascular Research, Royal Holloway, University of London, London, UK.
Sapna SharmaInstitute of Cardiovascular Research, Royal Holloway, University of London, London, UK.
Pankaj SharmaInstitute of Cardiovascular Research, Royal Holloway, University of London, London, UK.
Royal Holloway University of London · GBAshford and St Peter's Hospitals NHS Foundation Trust · GBEpsom and St Helier University Hospitals NHS Trust · GBFrimley Health NHS Foundation Trust · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBecause of their high risk of stroke, anticoagulation therapy is recommended for most patients with atrial fibrillation (AF). The present study evaluated the use of anticoagulants in the community and in a hospital setting for patients with AF and its associations with stroke.

methodsPatients admitted with stroke to four major hospitals in County of Surrey, England were surveyed in the 2014-2016 Sentinel Stroke National Audit Programme. Descriptive statistics was used to summarise subject characteristics and χ² test to assess differences between categorical variables.

resultsA total of 3309 patients, 1656 men (mean age: 73.1 years±SD 13.2) and 1653 women (79.3 years±13.0) were admitted with stroke (83.3% with ischaemic, 15.7% haemorrhagic stroke and 1% unspecified). AF occurred more frequently (χ

conclusionsThe study highlights an existing burden for patients with stroke and reflects inadequate treatment of AF which results in an increased stroke burden. There is significant scope to improve the rates of anticoagulation.

Indexed as

RegistriesAgedAged, 80 and overAnticoagulantsAtrial FibrillationBrain IschemiaCross-Sectional StudiesFemaleHumansIntracranial HemorrhagesMaleMiddle AgedStrokeThrombolytic TherapyUnited KingdomAnticoagulantsadult cardiologycardiologystroke medicine

Identifiers

PMID29997144
PMCPMC6089275
OpenAlexW2832783883

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.