Evidence map›Paper›PMID 29997132›Full record

ArticleJournal of the American Heart Association2018

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study.

S Justin Thomas, John N Booth, Chen Dai, Xuelin Li, Norrina Allen, David Calhoun, April P Carson, Samuel Gidding, Cora E Lewis, James M Shikany and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 127 citations in OpenAlex.

  1. Trial
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  5. Usage and positivity rates of Alzheimer's disease biomarkers in a memory clinic.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  14. Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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  15. Tracking of blood pressure levels from childhood.Pediatric nephrology (Berlin, Germany) · 2025
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  18. Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

S Justin ThomasDepartment of Psychiatry, University of Alabama at Birmingham, AL sjthomas@uab.edu.
John N BoothDepartment of Epidemiology, University of Alabama at Birmingham, AL.
Chen DaiDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, AL.
Xuelin LiDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, AL.
Norrina AllenDepartment of Preventive Medicine, Northwestern University, Chicago, IL.
David CalhounDepartment of Medicine, University of Alabama at Birmingham, AL.
April P CarsonDepartment of Epidemiology, University of Alabama at Birmingham, AL.
Samuel GiddingNemours Cardiac Center, DuPont Hospital for Children, Wilmington, DE.
Cora E LewisDepartment of Epidemiology, University of Alabama at Birmingham, AL.
James M ShikanyDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, AL.
Daichi ShimboDepartment of Medicine, Columbia University, New York, NY.
Stephen SidneyDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, AL.
University of Alabama at Birmingham · USColumbia University · USDuPont (United States) · USKaiser Permanente · USNorthwestern University · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI W Timothy GARVEY · 2013 to 2026
$19.5M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS K24 HL125704NHLBI NIH HHS R01 HL117323NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundBlacks have higher blood pressure levels compared with whites beginning in childhood. Few data are available on racial differences in the incidence of hypertension from young adulthood through middle age. METHODS AND

resultsWe calculated the cumulative incidence of hypertension from age 18 to 55 years among participants in the CARDIA (Coronary Artery Risk Development in Young Adults) study. Incident hypertension was defined by the first visit with mean systolic blood pressure ≥130 mm Hg, mean diastolic blood pressure ≥80 mm Hg, or self-reported use of antihypertensive medication. Among 3890 participants without hypertension at baseline (aged 18-30 years), cumulative incidence of hypertension by age 55 years was 75.5%, 75.7%, 54.5%, and 40.0% in black men, black women, white men, and white women, respectively. Among participants with systolic blood pressure/diastolic blood pressure <110 and 70, 110 to 119/70 to 74, and 120 to 129/75 to 79 mm Hg at baseline, blacks were more likely than whites to develop hypertension: multivariable-adjusted hazard ratios 1.97 (95% confidence interval, 1.65, 2.35), 1.80 (95% confidence interval, 1.52, 2.14), and 1.59 (95% confidence interval, 1.31, 1.93), respectively. Parental history of hypertension and higher body mass index, serum uric acid, and systolic blood pressure/diastolic blood pressure categories were associated with a higher risk for hypertension among blacks and whites. A higher Dietary Approaches to Stop Hypertension diet adherence score was associated with a lower risk for hypertension in blacks and whites.

conclusionsRegardless of blood pressure level in young adulthood, blacks have a substantially higher risk for hypertension compared with whites through 55 years of age.

Indexed as

AdolescentAdultBlack or African AmericanDietary Approaches To Stop HypertensionFemaleHumansHypertensionIncidenceMaleMiddle AgedUnited StatesWhite PeopleYoung Adulthypertensionincidencerace

Identifiers

PMID29997132
PMCPMC6064834
OpenAlexW2834387971

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.