ArticleJournal of the American Heart Association2018
Nephron-Specific Disruption of Nitric Oxide Synthase 3 Causes Hypertension and Impaired Salt Excretion.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Pharmacologic disruption of HuR-RNA interactions prevents maladaptive tubular repair and AKI-to-CKD progression.American journal of physiology. Renal physiology · 2026Article
- Tubular deficiency of ABCA1 augments cholesterol- and NaAmerican journal of physiology. Renal physiology · 2024Article
- Article
- The effects of nitric oxide and 8-iso-prostaglandin F2α on chloride absorption in cortical thick ascending limb.Kidney research and clinical practice · 2022Article
- Article
- Genetic Modifications to Alter Blood Pressure Level.Biomedicines · 2022Review
- Circadian Control of Sodium and Blood Pressure Regulation.American journal of hypertension · 2021Review
- Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice.Scientific reports · 2021Article
- Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport.Frontiers in physiology · 2021Article
- Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2-Mediated Blood Pressure Reduction Independent of Cystogenesis.Journal of the American Society of Nephrology : JASN · 2020Article
- Diurnal Regulation of Renal Electrolyte Excretion: The Role of Paracrine Factors.Annual review of physiology · 2020Review
- Renal Dopamine Oxidation and Inflammation in High Salt Fed Rats.Journal of the American Heart Association · 2020Article
- Molecular regulation of NKCC2 in blood pressure control and hypertension.Current opinion in nephrology and hypertension · 2019Review
- The Drosophila Malpighian tubule as a model for mammalian tubule function.Current opinion in nephrology and hypertension · 2019Review
- Identification of NFAT5 as a transcriptional regulator of the EDN1 gene in collecting duct.American journal of physiology. Renal physiology · 2019Article
- Nephron-Specific Disruption of Nitric Oxide Synthase 3 Causes Hypertension and Impaired Salt Excretion.Journal of the American Heart Association · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIn vitro studies suggest that nephron nitric oxide synthase 3 (NOS3) modulates tubule Na METHODS AND
resultsTo assess nephron NOS3 relevance in vivo, knockout (KO) mice with doxycycline-inducible nephron-wide deletion of NOS3 were generated. During 1 week of salt loading, KO mice, as compared with controls, had higher arterial pressure and Na
conclusionsThese findings indicate that nephron NOS3 is involved in blood pressure regulation and urinary Na
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.