Evidence map›Paper›PMID 29997100›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018

[Efficacy of inactivated autologous porous bone flap and BAM bone-induced artificial bone for repairing skull defect in rats].

Chao-Min Wang, Tie-Jian Liu, Zhen-Hua Song, Xiao-Yu Guo, Da-Nian Wei, Cheng-Yong Liu

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chao-Min WangTreatment Center of Traumatic Injuries, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China. E-mail: 136340327@qq.com.
Tie-Jian Liu
Zhen-Hua Song
Xiao-Yu Guo
Da-Nian Wei
Cheng-Yong Liu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of BAM bone grafting combined with inactivated autologous porous bone flap in repairing skull defect in rats.

methodsSeventy-two Wistar rats with skull defect were randomly divided into control group, inactivated autologous bone flap group (AB group), BAM bone-induced artificial bone material group (BAM group), and inactivated autologous bone flap with BAM bone-induced artificial bone group (BAM+AB group). The bone healing was evaluated with micro-CT and the new bone formation was assessed with histological staining at 1, 2, and 3 months after modeling.

resultsInactivated porous bone flap combined with BAM bone-induced artificial bone effectively induced vascular and fibrous tissue regeneration and osteogenesis in the cranial defects. With the inactivated porous bone flap as the scaffold, BAM bone-induced artificial bone obviously promoted the restoration of the skull appearance in the rats with cranial defects.

conclusionInactivated autologous bone flap group and BAM bone-induced artificial bone material can promote skull healing and restoration of the original skull appearance, and can be used for reconstruction of the local anatomy of the skull surface.

Indexed as

Bone SubstitutesAnimalsBone RegenerationBone TransplantationOsteogenesisRandom AllocationRatsRats, WistarSkullWound HealingBone Substitutes

Identifiers

PMID29997100
PMCPMC6765716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.