SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2018
Head-to-head comparison of qSOFA and SIRS criteria in predicting the mortality of infected patients in the emergency department: a meta-analysis.
Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
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Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Screening tools for sepsis identification in paramedicine and other emergency contexts: a rapid systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2023Pooled it
- Age-adjusted quick Sequential Organ Failure Assessment score for predicting mortality and disease severity in children with infection: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- A randomised controlled trial comparing two protocols of preoperative antibiotics in patients with positive urine culture undergoing percutaneous nephrolithotomy.World journal of urology · 2023Trial
- Predicting deterioration of patients with early sepsis at the emergency department using continuous heart rate variability analysis: a model-based approach.Scandinavian journal of trauma, resuscitation and emergency medicine · 2023Trial
- Pain as an underrecognized geriatric syndrome in hospitalized older adults with major neurocognitive disorder: clinical correlates and outcomes.European geriatric medicine · 2026Observational
- The development and internal validation of a rating scale system in predicting renal stone bacteria culture positivity before PCNL: a cross-sectional study.Urolithiasis · 2026Article
- Multi-Marker Approach in Sepsis: A Clinical Role Beyond SOFA Score.Medicina (Kaunas, Lithuania) · 2026Article
- Shock index-modified qSOFA improves mortality risk stratification in patients with sepsis beyond conventional qSOFA.Frontiers in medicine · 2026Article
- Exploring proteomic signatures in sepsis and non-infectious systemic inflammatory response syndrome.PloS one · 2026Observational
- Review
- Observational
- A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis.Nature communications · 2025Article
- Diagnostic values of noradrenaline administered dose, procalcitonin (PCT) and blood lactic acid for septic shock.Journal of medical biochemistry · 2025Article
- The role of artificial intelligence in sepsis in the Emergency Department: a narrative review.Annals of translational medicine · 2025Review
- Is it necessary for patients with a positive urine culture to achieve a negative result after antimicrobial treatment before undergoing percutaneous nephrolithotomy?World journal of urology · 2025Article
- Investigating the time to blood culture positivity: why does it take so long?Journal of medical microbiology · 2025Article
- Accuracy of the Identification and Prognosis Prediction of SOFA-Based Sepsis-3 for Septic Patients in the Emergency Department Compared With Sepsis-2.Emergency medicine international · 2025Article
- Predictive performance of NEWS and qSOFA in immunocompromised sepsis patients at the emergency department.Infection · 2024Observational
- Adverse Outcomes of Patients with Non-Ventilator-Associated Hospital-Acquired Pneumonia (nvHAP)-A Single Centre Cohort Study.Infectious disease reports · 2024Article
- Exploiting the Features of Clinical Judgment to Improve Assessment of Disease Severity in the Emergency Department: An Acutelines Study.Journal of clinical medicine · 2024Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
backgroundRecently, the concept of sepsis was redefined by an international task force. This international task force of experts recommended using the quick Sequential Organ Failure Assessment (qSOFA) criteria instead of the systemic inflammatory response syndrome (SIRS) criteria to classify patients at high risk for death. However, the added value of these new criteria in the emergency department (ED) remains unclear. Thus, we performed this meta-analysis to determine the diagnostic accuracy of the qSOFA criteria in predicting mortality in ED patients with infections and compared the performance with that of the SIRS criteria.
methodsPubMed, EMBASE and Google Scholar (up to April 2018) were searched for related articles. A 2 × 2 contingency table was constructed according to mortality and qSOFA score (< 2 and ≥ 2) or SIRS score (< 2 and ≥ 2) in ED patients with infections. Two investigators independently assessed study eligibility and extracted data. We used a bivariate meta-analysis model to determine the prognostic value of qSOFA and SIRS in predicting mortality. We used the I
resultsEight studies with a total of 52,849 patients were included. A qSOFA score ≥ 2 was associated with a higher risk of mortality in ED patients with infections, with a pooled risk ratio (RR) of 4.55 (95% CI, 3.38-6.14) using a random-effects model (I
conclusionsA qSOFA score ≥ 2 and SIRS score ≥ 2 are strongly associated with mortality in ED patients with infections. However, it is also clear that qSOFA and SIRS have limitations as risk stratification tools for ED patients with infections.
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