Evidence map›Paper›PMID 29996517›Full record

ArticleHealthcare (Basel, Switzerland)2018

Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment.

Vivek Podder, Binod Dhakal, Gousia Ummae Salma Shaik, Kaushik Sundar, Madhava Sai Sivapuram, Vijay Kumar Chattu, Rakesh Biswas

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vivek PodderDepartment of Internal Medicine, Tairunnessa Memorial Medical College, Gazipur 1704, Bangladesh. drvivekpodder@gmail.com.ORCID 0000-0003-3103-3043
Binod DhakalDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. bdhakal@mcw.edu.
Gousia Ummae Salma ShaikDepartment of Internal Medicine, Kamineni Institute of Medical Sciences, Narketpally 508254, India. drshaiksalma@gmail.com.
Kaushik SundarDepartment of Neurology, Rajagiri Hospital, Chunanangamvely, Aluva 683112, India. skaushik85@gmail.com.
Madhava Sai SivapuramDepartment of Internal Medicine, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinaoutapalli 521101, India. madhavasai2011@gmail.com.
Vijay Kumar ChattuDepartment of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine 0000, Trinidad and Tobago. vijay.chattu@sta.uwi.edu.ORCID 0000-0001-9840-8335
Rakesh BiswasDepartment of Internal Medicine, Kamineni Institute of Medical Sciences, Narketpally 508254, India. rakesh7biswas@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrecision medicine aims to focus on meeting patient requirements accurately, optimizing patient outcomes, and reducing under-/overdiagnosis and therapy. We aim to offer a fresh perspective on accuracy driven “age-old precision medicine” and illustrate how newer case-based blended learning ecosystems (CBBLE) can strengthen the bridge between age-old precision approaches with modern technology and omics-driven approaches. METHODOLOGY: We present a series of cases and examine the role of precision medicine within a “case-based blended learning ecosystem” (CBBLE) as a practicable tool to reduce overdiagnosis and overtreatment. We illustrated the workflow of our CBBLE through case-based narratives from global students of CBBLE in high and low resource settings as is reflected in global health.

resultsFour micro-narratives based on collective past experiences were generated to explain concepts of age-old patient-centered scientific accuracy and precision and four macro-narratives were collected from individual learners in our CBBLE. Insights gathered from a critical appraisal and thematic analysis of the narratives were discussed. DISCUSSION AND

conclusionCase-based narratives from the individual learners in our CBBLE amply illustrate their journeys beginning with “age-old precision thinking” in low-resource settings and progressing to “omics-driven” high-resource precision medicine setups to demonstrate how the approaches, used judiciously, might reduce the current pandemic of over-/underdiagnosis and over-/undertreatment.

Indexed as

case studiesCBBLE (case-based-based blended learning ecosystem)high resource settinglow resource settingomics drivenoverdiagnosisovertreatmentprecision medicine

Identifiers

PMID29996517
PMCPMC6163835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.