Evidence map›Paper›PMID 29996476›Full record

Trial reportNutrients2018

A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias.

Pamela L Lutsey, Lin Y Chen, Anne Eaton, Melanie Jaeb, Kyle D Rudser, James D Neaton, Alvaro Alonso

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Review
  14. Magnesium-A More Important Role in CKD-MBD than We Thought.Diagnostics (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pamela L LutseyDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA. Lutsey@umn.edu.ORCID 0000-0002-1572-1340
Lin Y ChenCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA. chenx484@umn.edu.
Anne EatonDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. eato0055@umn.edu.
Melanie JaebDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA. jaebx008@umn.edu.
Kyle D RudserDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. rudser@umn.edu.
James D NeatonDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. jim@ccbr.umn.edu.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA. alvaro.alonso@emory.edu.ORCID 0000-0002-2225-8323
University of Minnesota · USEmory University · US

Funding

American Heart Association-American Stroke Association 16EIA26410001
6 · The paper itself

Abstract

Low magnesium may increase the risk of atrial fibrillation. We conducted a double-blind pilot randomized trial to assess adherence to oral magnesium supplementation (400 mg of magnesium oxide daily) and a matching placebo, estimate the effect on circulating magnesium concentrations, and evaluate the feasibility of using an ambulatory heart rhythm monitoring device (ZioPatch) for assessing premature atrial contractions. A total of 59 participants were randomized; 73% were women, and the mean age was 62 years. A total of 98% of the participants completed the follow-up. In the magnesium supplement group, 75% of pills were taken, and in the placebo group, 83% were taken. The change in magnesium concentrations was significantly greater for those given the magnesium supplements than for those given the placebo (0.07; 95% confidence interval: 0.03, 0.12 mEq/L;

Indexed as

Dietary SupplementsAdministration, OralAgedAnti-Arrhythmia AgentsAtrial FibrillationAtrial Premature ComplexesDouble-Blind MethodElectrocardiography, AmbulatoryFeasibility StudiesFemaleHeart RateHumansMagnesium OxideMaleMedication AdherenceMiddle AgedAnti-Arrhythmia AgentsMagnesium Oxideatrial fibrillationglucosemagnesiumrandomized controlled trial

Identifiers

PMID29996476
PMCPMC6073799
OpenAlexW2767287178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.