ArticleCerebrovascular diseases extra2018
Cerebral Haemodynamics following Acute Ischaemic Stroke: Effects of Stroke Severity and Stroke Subtype.
Article in Cerebrovascular diseases extra, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessment of cerebral autoregulation in stroke: A systematic review and meta-analysis of studies at rest.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
- Transcranial ultrasound with electrical stimulation of the cerebello-parietal nucleus on cerebral blood flow and limb function in patients with stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Trial
- Article
- Pulsatility index: Insights into post-stroke haemodynamics.Neuroscience insights · 2026Review
- Neuraxial anesthesia for non-neurological emergency surgery in a patient with acute ischemic stroke: a case report.International journal of emergency medicine · 2024Article
- A Multi-Parametric Approach for Characterising Cerebral Haemodynamics in Acute Ischaemic and Haemorrhagic Stroke.Healthcare (Basel, Switzerland) · 2024Article
- Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study.Journal of the American Heart Association · 2024Article
- Neuroprotective Effect of Platinum Nanoparticles Is Not Associated with Their Accumulation in the Brain of Rats.Journal of functional biomaterials · 2023Article
- The utility of therapeutic hypothermia on cerebral autoregulation.Journal of intensive medicine · 2023Review
- Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Review
- Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Review
- Observation of the Effect of TTM-Based Health Information Behavior Combined with Continuous Nursing on Cognitive and Motor Function, Living Ability, and the Quality of Life of Cerebral Stroke Patients.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Assessment of cognitive impairment after acute cerebral infarction with T1 relaxation time measured by MP2RAGE sequence and cerebral hemodynamic by transcranial Doppler.Frontiers in neurology · 2022Article
- Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation.Physiological reviews · 2021Review
- Cerebral Autoregulation in Ischemic Stroke: From Pathophysiology to Clinical Concepts.Brain sciences · 2021Review
- Implication of MicroRNA503 in Brain Endothelial Cell Function and Ischemic Stroke.Translational stroke research · 2020Article
- Pathophysiological and clinical considerations in the perioperative care of patients with a previous ischaemic stroke: a multidisciplinary narrative review.British journal of anaesthesia · 2020Review
- Dynamic Cerebral Autoregulation in Embolic Stroke of Undetermined Source.Frontiers in physiology · 2020Article
- Corneal nerve and endothelial cell damage in patients with transient ischemic attack and minor ischemic stroke.PloS one · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute ischaemic stroke (AIS) patients often show impaired cerebral autoregulation (CA). We tested the hypothesis that CA impairment and other alterations in cerebral haemodynamics are associated with stroke subtype and severity.
methodsAIS patients (n = 143) were amalgamated from similar studies. Data from baseline (< 48 h stroke onset) physiological recordings (beat-to-beat blood pressure [BP], cerebral blood flow velocity (CBFV) from bilateral insonation of the middle cerebral arteries) were calculated for mean values and autoregulation index (ARI). Differences were assessed between stroke subtype (Oxfordshire Community Stroke Project [OCSP] classification) and severity (National Institutes of Health Stroke Scale [NIHSS] score < 5 and 5-25). Correlation coefficients assessed associations between NIHSS and physiological measurements.
resultsThirty-two percent of AIS patients had impaired CA (ARI < 4) in affected hemisphere (AH) that was similar between stroke subtypes and severity. CBFV in AH was comparable between stroke subtype and severity. In unaffected hemisphere (UH), differences existed in mean CBFV between lacunar and total anterior circulation OCSP subtypes (42 vs. 56 cm•s-1, p < 0.01), and mild and moderate-to-severe stroke severity (45 vs. 51 cm•s-1, p = 0.04). NIHSS was associated with peripheral (diastolic and mean arterial BP) and cerebral haemodynamic parameters (CBFV and ARI) in the UH.
conclusionsAIS patients with different OCSP subtypes and severity have homogeneity in CA capability. Cerebral haemodynamic measurements in the UH were distinguishable between stroke subtype and severity, including the association between deteriorating ARI in UH with stroke severity. More studies are needed to determine their clinical significance and to understand the determinants of CA impairment in AIS patients.
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