Evidence map›Paper›PMID 29995909›Full record

ArticlePloS one2018

Disparities by race, age, and sex in the improvement of survival for lymphoma: Findings from a population-based study.

Fahad Mukhtar, Paolo Boffetta, Bashir Dabo, Jong Y Park, Chi T D Tran, Thuan V Tran, Huong Thi-Thanh Tran, Madison Whitney, Harvey A Risch, Linh C Le and 3 more

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Cancer statistics for adults aged 85 years and older, 2019.CA: a cancer journal for clinicians · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fahad MukhtarDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, United States of America.
Paolo BoffettaTisch Cancer Institute, Icahn School of Medicine, Mount Sinai School of Medicine, New York, NY, United States of America.
Bashir DaboDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, United States of America.
Jong Y ParkDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States of America.
Chi T D TranVietnam Colorectal Cancer and Research Program, Vinmec Healthcare System, Hanoi, Vietnam.
Thuan V TranVietnam National Cancer Hospital, Hanoi, Vietnam.
Huong Thi-Thanh TranVietnam National Cancer Hospital, Hanoi, Vietnam.
Madison WhitneyDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, United States of America.
Harvey A RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT, United States of America.
Linh C LeVinmec University of Health Sciences Project, Vinmec Healthcare System, Hanoi, Vietnam.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States of America.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States of America.
Hung N LuuDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States of America.ORCID 0000-0002-2172-1849

Funding

Regional Center of Research Excellence in Cancer and Other Non-Communicable Disease Epidemiology and Prevention in VietnamP20CA210300 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU, TRAN, THUAN · 2016 to 2017
$549k
NCI NIH HHS P20 CA210300
6 · The paper itself

Abstract

objectiveTo evaluate improvement in survival of lymphoma patients from 1990 to 2014, stratified by age, sex and race using Surveillance Epidemiology and End-Result Survey Program (SEER) data. STUDY DESIGN AND

settingWe identified 113,788 incident lymphoma cases from nine SEER cancer registries were followed up for cause-specific mortality from lymphoma. Cox proportional hazard regression was used to estimate hazard ratios (HRs) and their respective 95% confidence interval (CIs) for various time periods within groups stratified by race, age and sex.

resultsFive-year survival for Hodgkin's lymphoma (HL) was 89% for patients 20-49 years of age. For this age group, compared to 1990-1994, survival significantly improved in 2000-2004 (HR = 0.65; 95% CI: 0.54-0.78), 2005-2009 (HR = 0.46, 95% CI: 0.38-0.57) and 2010-2014 (HR = 0.29, 95% CI: 0.20-0.41). Hodgkin's lymphoma patients aged 75-85 years had 5-year survival of 37% and in these patients, compared to 1990-1994, survival only improved from 2005 onward (HR = 0.67, 95% CI: 0.50-0.90). In patients with non-Hodgkin's Lymphoma (NHL), all age groups showed survival improvements between 1990-1994 period and 2010-2014 period. Improvements in HL and NHL survival were seen for all race categories and both genders.

conclusionSurvival among US lymphoma patients has improved substantially between 1990-1994 period and 2010-2014 period, though disease-specific mortality was still higher in older age groups.

Indexed as

AdultAge FactorsFemaleHodgkin DiseaseHumansMaleMiddle AgedPopulation GroupsSex FactorsSurvival Analysis

Identifiers

PMID29995909
PMCPMC6040734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.