ArticleObstetrics and gynecology2018
Fatal and Nonfatal Overdose Among Pregnant and Postpartum Women in Massachusetts.
Article in Obstetrics and gynecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07642947 (A Digitally Enhanced Model of Peer Doula Support for Substance Use Disorder and Peripartum Care), which is not on this map. Cited by 169 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Digitally Enhanced Model of Peer Doula Support for Substance Use Disorder and Peripartum Care
Who cites it
169 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mental disorder and opioid overdose: a systematic review.Social psychiatry and psychiatric epidemiology · 2022Pooled it
- Factors Associated With Opioid-Involved Overdose: Descriptive Data From a Randomized Controlled Trial Evaluating Extended-Release Buprenorphine for Perinatal Opioid Use Disorder.Substance use & addiction journal · 2026Trial
- Patient navigation for pregnant individuals with opioid use disorder: Results of a randomized multi-site pilot trial.Addiction (Abingdon, England) · 2024Trial
- Collaborative care programs for pregnant and postpartum individuals with opioid use disorder: Organizational characteristics of sites participating in the NIDA CTN0080 MOMs study.Journal of substance use and addiction treatment · 2023Trial
- Nonfatal Overdoses Among Pregnant Individuals With Opioid Use Disorder.Obstetrics and gynecology · 2023Trial
- Social determinants of health associated with newly documented opioid-related postpartum readmissions.Pregnancy (Hoboken, N.J.) · 2026Article
- Enhancing Postpartum Care for Incarcerated People With Opioid Use Disorder: A Multimodal Intervention for Jail Staff.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2026Article
- Duration of Medication Use for Opioid Use Disorder and Risk of Postpartum Overdose and Death.JAMA network open · 2026Article
- Guidance on providing telebehavioral health care for perinatal populations: An assessment of resources and gaps.Archives of women's mental health · 2026Article
- Association of Continuous Medicaid Eligibility With Postpartum Coverage and Opioid Use Disorder Treatment.American journal of preventive medicine · 2026Article
- Infant caregiving, relational factors, mood, and pain in perinatal opioid use disorder: A prospective cohort with ecological momentary assessment.Addictive behaviors · 2026Article
- Adverse maternal and neonatal effects associated with perinatal xylazine exposure: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Examining buprenorphine compared to methadone for likelihood of overdose during pregnancy, 2014-2021.Pregnancy (Hoboken, N.J.) · 2026Article
- Experiences of pregnant and postpartum people of color engaged in a randomized clinical trial of medication to treat opioid use disorder during pregnancy: A "Positive Outliers" analysis.Journal of substance use and addiction treatment · 2026Article
- Comparing Pregnant and Postpartum Client and Provider Feedback on a Digital Health Intervention for Substance Use Recovery: User-Centered Design Approach.JMIR formative research · 2026Article
- Testing the effectiveness of Family Spirit Strengths (FSS) - a culturally informed intervention designed to prevent mental health and substance misuse for indigenous families through home visiting.BMC public health · 2026Article
- An intervention mapping approach to closing the gap in maternal OUD and infant NOWS care: a study protocol.BMC pregnancy and childbirth · 2026Article
- Bringing MOUD "In House": Implementing an Internal MOUD Program During Pregnancy in a State Prison.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2026Article
- Navigating opioid use disorder treatment for pregnant and parenting people: composite narratives for policy action.Substance abuse treatment, prevention, and policy · 2026Article
- Postpartum retention in opioid agonist treatment for opioid dependence: A population-based cohort study.Archives of women's mental health · 2026Article
109 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveTo estimate fatal and nonfatal opioid overdose events in pregnant and postpartum women in Massachusetts, comparing rates in individuals receiving and not receiving pharmacotherapy for opioid use disorder (OUD).
methodsWe conducted a population-based retrospective cohort study using linked administrative and vital statistics databases in Massachusetts to identify women with evidence of OUD who delivered a liveborn neonate in 2012-2014. We described maternal sociodemographic, medical, and substance use characteristics, computed rates of opioid overdose events in the year before and after delivery, and compared overdose rates by receipt of pharmacotherapy with methadone or buprenorphine in the prenatal and postpartum periods.
resultsAmong 177,876 unique deliveries, 4,154 (2.3%) were to women with evidence of OUD in the year before delivery, who experienced 242 total opioid-related overdose events (231 nonfatal, 11 fatal) in the year before or after delivery. The overall overdose rate was 8.0 per 100,000 person-days. Overdoses were lowest in the third trimester (3.3/100,000 person-days in the third trimester) and then increased in the postpartum period with the highest overdose rate 7-12 months after delivery (12.3/100,000 person-days). Overall, 64.3% of women with evidence of OUD in the year before delivery received any pharmacotherapy in the year before delivery. Women receiving pharmacotherapy had reduced overdose rates in the early postpartum period.
conclusionPregnant women in Massachusetts have high rates of OUD. The year after delivery is a vulnerable period for women with OUD. Additional longitudinal supports and interventions tailored to women in the first year postpartum are needed to prevent and reduce overdose events.
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Registered trials
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