ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2018
Impact of age on the development of fatigue during large and small muscle mass exercise.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single- and double-leg cycling in older adults.Experimental physiology · 2026Article
- The efficacy and physiological bases of small muscle mass exercise in health and disease.Experimental physiology · 2026Review
- The independent effects of age and sex in performance fatigability profile after a ramp incremental cycling test.European journal of applied physiology · 2025Article
- There Are No Differences in Startle Conditioned Cervicomedullary Motor Evoked Potentials Across Isometric, Concentric, and Eccentric Muscle Actions at the Same Absolute Force Output.The European journal of neuroscience · 2025Article
- Effects of fatigue on motor unit characteristics in isometric elbow contractions across age groups.Frontiers in neuroscience · 2025Article
- Factors affecting seafarers' fatigue: a scoping review.Frontiers in public health · 2025Article
- Comparison of Lower-Limb Muscle Synergies Between Young and Old People During Cycling Based on Electromyography Sensors-A Preliminary Cross-Sectional Study.Sensors (Basel, Switzerland) · 2024Article
- Measuring objective fatigability and autonomic dysfunction in clinical populations: How and why?Frontiers in sports and active living · 2023Review
- Article
- Impact of aging on the work of breathing during exercise in healthy men.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Fatigue development and perceived response during self-paced endurance exercise: state-of-the-art review.European journal of applied physiology · 2021Review
- Heart failure with preserved ejection fraction diminishes peripheral hemodynamics and accelerates exercise-induced neuromuscular fatigue.American journal of physiology. Heart and circulatory physiology · 2021Article
- Effect of aging on H-reflex response to fatigue.Experimental brain research · 2020Article
- Neuromuscular fatigue during whole body exercise.Current opinion in physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
To examine the impact of aging on neuromuscular fatigue following cycling (CYC; large active muscle mass) and single-leg knee-extension (KE; small active muscle mass) exercise, 8 young (25 ± 4 years) and older (72 ± 6 years) participants performed CYC and KE to task failure at a given relative intensity (80% of peak power output). The young also matched CYC and KE workload and duration of the old (iso-work comparison). Peripheral and central fatigue were quantified via pre-/postexercise decreases in quadriceps twitch torque (∆Q
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.