Evidence map›Paper›PMID 29995288›Full record

ArticleJournal of neurovirology2018

Human parechovirus type 6 and Guillain-Barré syndrome: a case report.

Laura Pellegrinelli, S Gambara, R Micheli, S Binda, E Fazzi, E Pariani

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Triggers of Guillain-Barré Syndrome:International journal of molecular sciences · 2022
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laura PellegrinelliDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy. laura.pellegrinelli@unimi.it.ORCID 0000-0003-2344-6032
S GambaraUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, Italy.
R MicheliUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, Italy.
S BindaDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy.
E FazziUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, Italy.
E ParianiDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A previously healthy 6-year-old boy was admitted to hospital with hypotonia and hyposthenia of lower limbs. Electromyography and slow motor nerve conduction velocity test identified a lower limb acute motor axonal neuropathy. Brain and spinal cord magnetic resonance imaging demonstrated multifocal cortical gray matter lesions in both cerebral hemispheres consistent with gray matter acute disseminated encephalitis otherwise with viral/Mycoplasma pneumoniae encephalitis, and signs of involvement of anterior nerve roots of the cauda equina consistent with Guillain-Barré syndrome. The patient resulted negative to routinely bacterial and viral investigations but positive to human parechovirus that sequence analyses confirmed as type 6. Intravenous immunoglobulins and methylprednisolone treatment were administered but did not relieve the symptoms of Guillain-Barré syndrome. The disease improved gradually over the next 3-month follow-up with a complete remission of both central and peripheral nervous system symptoms.

Indexed as

ChildGuillain-Barre SyndromeHumansMaleParechovirusPicornaviridae InfectionsAcute flaccid paralysis surveillanceGuillain-Barré syndromeHuman parechovirusMolecular characterization

Identifiers

PMID29995288
OpenAlexW2879874504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.