Evidence map›Paper›PMID 29995029›Full record

ArticleOrganic & biomolecular chemistry2018

Sterically shielded tetrazoles for a fluorogenic photoclick reaction: tuning cycloaddition rate and product fluorescence.

Peng An, Qing Lin

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Bioorthogonal Reactions in Bioimaging.Topics in current chemistry (Cham) · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Photoclick Chemistry: A Bright Idea.Chemical reviews · 2021
    Review
  7. Light-Triggered Click Chemistry.Chemical reviews · 2021
    Review
  8. Bioorthogonal oncometabolite ligation.Methods in enzymology · 2019
    Article
  9. Hydrophilic azaspiroalkenes as robust bioorthogonal reporters.Chemical communications (Cambridge, England) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peng AnDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA. qinglin@buffalo.edu.
Qing Lin

Funding

Development and Applications of Photoinducible Bioorthogonal ChemistryR01GM085092 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LIN, QING · 2009 to 2017
$2.8M
NIGMS NIH HHS R01 GM085092
6 · The paper itself

Abstract

A panel of sterically shielded tetrazoles with different N-aryl groups were synthesized and subsequently evaluated in the photoinduced tetrazole-alkene cycloaddition reaction. It was found that increase in the HOMO energy of the corresponding nitrile imines leads to a faster cycloaddition reaction along with a red shift in the fluorescence emission of the pyrazoline cycloadduct.

Indexed as

Click ChemistryCyclizationFluorescenceFluorescent DyesPyrazolesTetrazolesFluorescent DyesPyrazolesTetrazoles

Identifiers

PMID29995029
PMCPMC6059988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.