Evidence map›Paper›PMID 29995016›Full record

ArticleThe international journal of occupational and environmental medicine2018

Mercury-induced Oxidative Stress May Adversely Affect Pregnancy Outcome among Dental Staff: A Cohort Study.

Aziza El-Badry, Mohamed Rezk, Hanan El-Sayed

Open access · diamondAbstract read
In one paragraph

Article in The international journal of occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Australasian recurrent pregnancy loss clinical management guideline 2024, part II.The Australian & New Zealand journal of obstetrics & gynaecology · 2024
    Guideline
  4. Maternal Mercury Exposure and Hypertensive Disorders of Pregnancy: A Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Pooled it
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  16. Occupational and environmental mercury exposure and human reproductive health - a review.Journal of the Turkish German Gynecological Association · 2022
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  19. Brief Review of Endometriosis and the Role of Trace Elements.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aziza El-BadryDepartment of Public Health and Community Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt. m_rezk9207@yahoo.com.
Mohamed RezkDepartment of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Hanan El-SayedDepartment of Pediatrics, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Menoufia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental staff may be at increased risk of adverse pregnancy outcome secondary to their chronic exposure to mercury.

objectiveTo investigate obstetric outcome among dental staff and explore the oxidative stress induced by mercury exposure.

methodsA cohort of 64 pregnant dental staff (exposed group) and 60 pregnant employees (non-exposed group) were studied. Urinary mercury level and blood antioxidant activity were measured. Participants were followed to assess their obstetric outcome.

resultsThe exposed group had a higher mean urinary mercury level and a lower blood antioxidant activity during the three trimesters compared to non-exposed group (p<0.001). Women in the exposed group were experienced more frequently spontaneous abortion and pre-eclampsia (p<0.05). Babies born to the women in the exposed group tended to be smaller for gestational age compared to those of non-exposed group (p<0.001).

conclusionPregnant dental staff suffered higher odds of developing spontaneous abortion and pre-eclampsia and giving birth to babies smaller for gestational age. This may be linked to oxidative stress induced by exposure to mercury.

Indexed as

Dental StaffPregnancy OutcomeAdultCohort StudiesFemaleHumansMaternal ExposureMercuryMercury PoisoningOccupational ExposureOxidative StressPre-EclampsiaPregnancyYoung AdultMercuryAntioxidantsDental staffGlutathione peroxidaseMercury poisoningOxidative stressPregnancy outcomeSuperoxide dismutase

Identifiers

PMID29995016
PMCPMC6466979
OpenAlexW2884765408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.