ArticleTransplantation2019
Gender Differences in Medication Adherence Among Adolescent and Young Adult Kidney Transplant Recipients.
Article in Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex and gender as predictors for allograft and patient-relevant outcomes after kidney transplantation.The Cochrane database of systematic reviews · 2024Pooled it
- Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients.The Cochrane database of systematic reviews · 2022Pooled it
- Prevalence of non-adherence to antihypertensive medication in Asia: a systematic review and meta-analysis.International journal of clinical pharmacy · 2021Pooled it
- Trial
- Randomized pilot trial of praise text messages to improve medication adherence among adolescents and young adults with liver transplants.Pediatric transplantation · 2022Trial
- Association between day of the week and medication adherence among adolescent and young adult kidney transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Trial
- Factors Affecting Medical Appointment Adherence among Adolescents and Young Adults with Kidney Disease: A Longitudinal Cohort Study.Journal of pediatrics. Clinical practice · 2026Article
- Low adherence to topical therapy in adults with atopic dermatitis: A cross-sectional study.JAAD international · 2026Article
- Burden of infectious diseases in children during the first year after solid organ transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Reduced Access to Second Kidney Transplantation Among Adolescent Girls.Kidney international reports · 2025Article
- Transition from pediatric to adult care in thoracic transplantation-Challenges and opportunities.JHLT open · 2025Article
- Medication Adherence Status and Influencing Factors in Adolescent Kidney Transplant Recipients.Pediatric transplantation · 2025Article
- Role of Educational Level in Kidney Transplant Outcomes.Biomedicines · 2025Article
- Predictors of Treatment Adherence in Kidney Transplant Patients: A Systematic Review of the Literature.Journal of clinical medicine · 2025Review
- Resilience, Post-Traumatic Growth, and Transplant Effects-Gender Differences Following Liver Transplantation: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Subsequent kidney transplant after pediatric heart transplant: Prevalence and risk factors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- A pharmacist-led intervention to improve kidney transplant recipient outcomes and identify patients at risk of highly variable trough tacrolimus levels: a cohort study.European journal of hospital pharmacy : science and practice · 2024Article
- The Effects of Race, Ethnicity, and Gender on Predictors of Asthma Medication Adherence among Early High School Students.Children's health care : journal of the Association for the Care of Children's Health · 2024Article
- A nationwide pharmacovigilance investigation on trends and seriousness of adverse events induced by anti-obesity medication.Journal of global health · 2023Article
- Association between health-related quality of life and nonadherence to antihypertensive medication.Nursing open · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAmong kidney transplant recipients, gender differences in medication adherence may contribute to higher graft failure risks observed in girls and young women compared with boys and young men. Our aim was to determine whether adherence differs by gender, and whether gender differences vary by age in adolescent and young adult kidney transplant recipients.
methodsWe examined data from the 3-month run-in period (no intervention) of the randomized Teen Adherence in Kidney transplant Effectiveness of Intervention trial. Adherence was monitored using electronic pillboxes in 136 patients (11-24 y) followed in 8 transplant centers in Canada and the United States. We used ordinal logistic regression with generalized estimating equations to estimate the association between gender and each of daily taking (proportion of prescribed doses taken) and timing (proportion of prescribed doses taken on time) adherence, considering effect modification by age (11-16 y vs 17-24 y).
resultsNo difference in taking adherence was observed by gender among participants aged 11 to 16 years (odds ratio [OR], 0.92; 95% confidence interval [CI], 0.55-1.54), whereas among participants aged 17 to 24 years, women had significantly greater odds of higher taking adherence scores (OR, 3.03; 95% CI, 1.20-7.66) than men. Results were similar for timing adherence, with no difference among participants aged 11 to 16 years (OR, 1.03; 95% CI, 0.65-1.63) but a greater odds of higher timing adherence scores in women than in men among participants aged 17 to 24 years (OR, 3.26; 95% CI, 1.43-7.45). There were no differences in adherence assessed by self-report or SD of tacrolimus trough levels.
conclusionsGender differences in adherence vary by age. Whereas younger adolescents show no adherence differences by gender, young women show much better adherence than young men.
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