Evidence map›Paper›PMID 29994913›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Setting Global Research Priorities in Pediatric and Adolescent HIV Using the Child Health and Nutrition Research Initiative (CHNRI) Methodology.

Cadi Irvine, Alice Armstrong, Jason M Nagata, Nigel Rollins, Diddie Schaaf, Meg Doherty, Martina Penazzato, Marissa Vicari

Open access · hybridAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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  8. Making Implementation Science Work for Children and Adolescents Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  9. A Global Research Agenda for Pediatric HIV.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  10. A Global Research Agenda for Adolescents Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  11. Ensuring Children and Adolescents Are Not Left Behind.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  12. Minding the Gap: Setting Research Priorities Related to HIV Testing, Treatment, and Service Delivery Among Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Cadi IrvineHIV Programmes and Advocacy, International AIDS Society, Geneva, Switzerland.
Alice ArmstrongHIV Programmes and Advocacy, International AIDS Society, Geneva, Switzerland.
Jason M NagataDivision of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, CA.
Nigel RollinsDepartment of Maternal, Newborn, Child and Adolescent Health, World Health Organization, Geneva, Switzerland.
Diddie SchaafHIV Programmes and Advocacy, International AIDS Society, Geneva, Switzerland.
Meg DohertyDepartment of HIV and Global Hepatitis Programme, World Health Organization, Geneva, Switzerland.
Martina PenazzatoDepartment of HIV and Global Hepatitis Programme, World Health Organization, Geneva, Switzerland.
Marissa VicariHIV Programmes and Advocacy, International AIDS Society, Geneva, Switzerland.
World Health Organization · CHInternational AIDS Society · CHUniversity of California, San Francisco · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundWHO and the Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) of the International AIDS Society (IAS) led a collaborative process to set global prioritized research agendas, aiming to focusing future research, funding, and stakeholder's efforts. This study describes the methodology used to establish the research agendas.

methodsThe Child Health and Nutrition Research Initiative methodology was adapted in parallel exercises on pediatric and adolescent HIV. After definition of scope by an expert working group, priority questions were collected from stakeholders through an online survey. Submitted questions were coded, analyzed, and collated. The same respondents were asked to score the collated lists through a second online survey. The top 10 ranked questions per thematic area (testing, treatment, and service delivery) were reviewed and priority themes developed with consideration of existing policy, systematic reviews, and planned, ongoing, and recently published research.

resultsA total of 375 respondents submitted 1735 priority research questions. The majority of respondents were from Africa; 55% self-identified as researchers. The final collated lists included 51 and 61 research questions for pediatric and adolescent HIV, respectively. The response rate for the second survey was 48%. The final research agendas include 5 priority research themes per area, discussed in 2 separate publications.

conclusionsTo date, this is the largest example of the Child Health and Nutrition Research Initiative method in pediatric and adolescent HIV in terms of stakeholders reached, and the first to incorporate top thematic areas based on current evidence. Its impact on improving outcomes for these populations will require strong political and financial commitment.

Indexed as

Adolescent HealthChild HealthGlobal HealthHealth PrioritiesResearchAdolescentChildFemaleHIV InfectionsHumansMaleNutritional StatusOnline SystemsPediatricsResearch DesignSurveys and Questionnaires

Identifiers

PMID29994913
PMCPMC6075898
OpenAlexW2884986921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.