ArticleIEEE transactions on biomedical circuits and systems2018
A Bidirectional-Current CMOS Potentiostat for Fast-Scan Cyclic Voltammetry Detector Arrays.
Article in IEEE transactions on biomedical circuits and systems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Development of a Smart Wireless Multisensor Platform for an Optogenetic Brain Implant.Sensors (Basel, Switzerland) · 2024Article
- A 512-Ch Dual-Mode Microchip for Simultaneous Measurements of Electrophysiological and Neurochemical Activities.Biosensors · 2023Article
- Wireless, Battery-Free Implants for Electrochemical Catecholamine Sensing and Optogenetic Stimulation.ACS nano · 2023Article
- On-Chip Cyclic Voltammetry Measurements Using a Compact 1024-Electrode CMOS IC.Analytical chemistry · 2021Article
- Quantifying neurotransmitter secretion at single-vesicle resolution using high-density complementary metal-oxide-semiconductor electrode array.Nature communications · 2021Article
- Massively parallel microwire arrays integrated with CMOS chips for neural recording.Science advances · 2020Article
- Drug testing complementary metal-oxide-semiconductor chip reveals drug modulation of transmitter release for potential therapeutic applications.Journal of neurochemistry · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A potentiostat circuit for the application of bipolar electrode voltages and detection of bidirectional currents using a microelectrode array is presented. The potentiostat operates as a regulated-cascode amplifier for positive input currents, and as an active-input regulated-cascode mirror for negative input currents. This topology enables constant-potential amperometry and fast-scan cyclic voltammetry (FSCV) at microelectrode arrays for parallel recording of quantal release events, electrode impedance characterization, and high-throughput drug screening. A 64-channel FSCV detector array, fabricated in a 0.5-$\mu$m, 5-V CMOS process, is also demonstrated. Each detector occupies an area of 45 $\mu$m $\times$ 30 $\mu$m and consists of only 14 transistors and a 50-fF integrating capacitor. The system was validated using prerecorded input stimuli from actual FSCV measurements at a carbon-fiber microelectrode.
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Registered trials
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