Evidence map›Paper›PMID 29994675›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2018

Field Characterization and Compensation of Vibrational Nonuniformity for a 256-Element Focused Ultrasound Phased Array.

Mohamed A Ghanem, Adam D Maxwell, Wayne Kreider, Bryan W Cunitz, Vera A Khokhlova, Oleg A Sapozhnikov, Michael R Bailey

Abstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. A Fully Populated Transrectal Array for Boiling Histotripsy Ablation of the Prostate.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  2. xDDx: A Numerical Toolbox for Ultrasound Transducer Characterization and Design With Acoustic Holography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  3. Article
  4. Treatment Planning and Aberration Correction Algorithm for HIFU Ablation of Renal Tumors.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Article
  5. Enhancement of Boiling Histotripsy by Steering the Focus Axially During the Pulse Delivery.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  6. Dual-Mode 1-D Linear Ultrasound Array for Image-Guided Drug Delivery Enhancement Without Ultrasound Contrast Agents.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  7. Comparative Characterization of Nonlinear Ultrasound Fields Generated by Sonalleve V1 and V2 MR-HIFU Systems.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  8. Article
  9. Quantitative Assessment of Boiling Histotripsy Progression Based on Color Doppler Measurements.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  10. Article
  11. Article
  12. mSOUND: An Open Source Toolbox for Modeling Acoustic Wave Propagation in Heterogeneous Media.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  13. A Prototype Therapy System for Boiling Histotripsy in Abdominal Targets Based on a 256-Element Spiral Array.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  14. Phase-Aberration Correction for HIFU Therapy Using a Multielement Array and Backscattering of Nonlinear Pulses.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  15. Article
  16. Article
  17. Noninvasive acoustic manipulation of objects in a living body.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed A Ghanem
Adam D Maxwell
Wayne Kreider
Bryan W Cunitz
Vera A Khokhlova
Oleg A Sapozhnikov
Michael R Bailey

Funding

SWL AND RENAL INJURY AND STONE COMMINUTIONP01DK043881 · NIDDK · UNIVERSITY OF WASHINGTON · PI BAILEY, MICHAEL R · 1994 to 2023
$33.5M
Nonlinear Acoustics in Calibration/Metrology of High Intensity Focused UltrasoundR01EB007643 · NIBIB · UNIVERSITY OF WASHINGTON · PI KHOKHLOVA, VERA · 2008 to 2020
$6.9M
Strategies in therapeutic ultrasound for predicting in situ fields and quantifying the impact of tissue inhomogeneitiesR01EB025187 · NIBIB · UNIVERSITY OF WASHINGTON · PI SAPOZHNIKOV, OLEG · 2018 to 2021
$2.1M
Noninvasive fragmentation of urinary calculi with focused ultrasound burstsK01DK104854 · NIDDK · UNIVERSITY OF WASHINGTON · PI MAXWELL, ADAM DOUGLAS · 2015 to 2019
$686k
NIBIB NIH HHS R01 EB007643NIBIB NIH HHS R01 EB025187NIDDK NIH HHS K01 DK104854NIDDK NIH HHS P01 DK043881
6 · The paper itself

Abstract

Multielement focused ultrasound phased arrays have been used in therapeutic applications to treat large tissue volumes by electronic steering of the focus, to target multiple simultaneous foci, and to correct aberration caused by inhomogeneous tissue pathways. There is an increasing interest in using arrays to generate more complex beam shapes and corresponding acoustic radiation force patterns for manipulation of particles such as kidney stones. Toward this end, experimental and computational tools are needed to enable accurate delivery of desired transducer vibrations and corresponding ultrasound fields. The purpose of this paper was to characterize the vibrations of a 256-element array at 1.5 MHz, implement strategies to compensate for variability, and test the ability to generate specified vortex beams that are relevant to particle manipulation. The characterization of the array output was performed in water using both element-by-element measurements at the focus of the array and holography measurements for which all the elements were excited simultaneously. Both methods were used to quantify each element's output so that the power of each element could be equalized. Vortex beams generated using both compensation strategies were measured and compared to the Rayleigh integral simulations of fields generated by an idealized array based on the manufacturer's specifications. Although both approaches improved beam axisymmetry, compensation based on holography measurements had half the error relative to the simulation results in comparison to the element-by-element method.

Indexed as

Equipment DesignHolographyTransducersUltrasonographyVibration

Identifiers

PMID29994675
PMCPMC6344030

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.