Evidence map›Paper›PMID 29994560›Full record

ArticleIEEE transactions on pattern analysis and machine intelligence2019

Semi-Supervised Discriminative Classification Robust to Sample-Outliers and Feature-Noises.

Ehsan Adeli, Kim-Han Thung, Le An, Guorong Wu, Feng Shi, Tao Wang, Dinggang Shen

Abstract read
In one paragraph

Article in IEEE transactions on pattern analysis and machine intelligence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Logistic Regression Confined by Cardinality-Constrained Sample and Feature Selection.IEEE transactions on pattern analysis and machine intelligence · 2020
    Article
  9. Article
  10. Review
  11. Review
  12. Quantitative Trait Module-Based Genetic Analysis of Alzheimer's Disease.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ehsan Adeli
Kim-Han Thung
Le An
Guorong Wu
Feng Shi
Tao Wang
Dinggang Shen

Funding

Longitudinal Analysis for Early Diagnosis of Alzheimer's DiseaseK01AG049089 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2016 to 2019
$478k
NIA NIH HHS K01 AG049089
6 · The paper itself

Abstract

Discriminative methods commonly produce models with relatively good generalization abilities. However, this advantage is challenged in real-world applications (e.g., medical image analysis problems), in which there often exist outlier data points (sample-outliers) and noises in the predictor values (feature-noises). Methods robust to both types of these deviations are somewhat overlooked in the literature. We further argue that denoising can be more effective, if we learn the model using all the available labeled and unlabeled samples, as the intrinsic geometry of the sample manifold can be better constructed using more data points. In this paper, we propose a semi-supervised robust discriminative classification method based on the least-squares formulation of linear discriminant analysis to detect sample-outliers and feature-noises simultaneously, using both labeled training and unlabeled testing data. We conduct several experiments on a synthetic, some benchmark semi-supervised learning, and two brain neurodegenerative disease diagnosis datasets (for Parkinson's and Alzheimer's diseases). Specifically for the application of neurodegenerative diseases diagnosis, incorporating robust machine learning methods can be of great benefit, due to the noisy nature of neuroimaging data. Our results show that our method outperforms the baseline and several state-of-the-art methods, in terms of both accuracy and the area under the ROC curve.

Indexed as

Supervised Machine LearningAlgorithmsBrainDatabases, FactualDiscriminant AnalysisHumansImage Interpretation, Computer-AssistedNeurodegenerative DiseasesNeuroimagingROC Curve

Identifiers

PMID29994560
PMCPMC6050136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.