Evidence map›Paper›PMID 29993739›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2019

Development of Low Frequency (20-100 kHz) Clinically Viable Ultrasound Applicator for Chronic Wound Treatment.

Olivia Ngo, Evan Niemann, Vivinya Gunasekaran, Prabagar Sankar, Miriam Putterman, Alec Lafontant, Sumati Nadkarni, Rose Ann DiMaria-Ghalili, Michael Neidrauer, Leonid Zubkov and 3 more

Abstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Design of Point-of-Care Ultrasound Device to be Used in At-Home Setting-A Holistic Approach.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Olivia Ngo
Evan Niemann
Vivinya Gunasekaran
Prabagar Sankar
Miriam Putterman
Alec Lafontant
Sumati Nadkarni
Rose Ann DiMaria-Ghalili
Michael Neidrauer
Leonid Zubkov
Michael Weingarten
David J Margolis
Peter A Lewin
Drexel University · USUniversity of Pennsylvania · US

Funding

Enhanced ultrasound treatment of chronic wounds with monitoring of healing and quality of life outcomesR01NR015995 · NINR · DREXEL UNIVERSITY · PI LEWIN, PETER A. · 2016 to 2020
$3.4M
Acousto-optic Theragnostic Approach for Chronic Wound ManagementR01EB009670 · NIBIB · DREXEL UNIVERSITY · PI LEWIN, PETER A. · 2010 to 2013
$1.7M
NIBIB NIH HHS R01 EB009670NINR NIH HHS R01 NR015995
6 · The paper itself

Abstract

This paper details the systematic approach used to develop a viable clinical prototype of a therapeutic ultrasound applicator and discusses the rationale and deliberations that led to the design strategy. The applicator was specifically devised to treat chronic wounds and-to the best of the author's knowledge-is the first truly wearable device with a proven record of reducing healing time, directly translating to a reduction of healthcare costs. The prototype operates in the kHz (20-100) range of frequencies and uses noncavitational and nonthermal levels of ultrasound energy. Hence, in the absence of inertial cavitation and temperature elevation, the tissue-ultrasound interaction is considered to be dependent on stable cavitation (if any) and radiation force. The peak acoustic output pressure amplitude is limited to 55 kPa, corresponding to a spatial peak-temporal peak intensity of 100 mW/cm

Indexed as

AdolescentAdultAgedAged, 80 and overBandagesDiabetic FootEquipment DesignHumansMiddle AgedUltrasonic TherapyWound HealingYoung Adult

Identifiers

PMID29993739
PMCPMC6542367
OpenAlexW2804553949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.