Evidence map›Paper›PMID 29993636›Full record

ArticleIEEE transactions on visualization and computer graphics2019

Robust Tracing and Visualization of Heterogeneous Microvascular Networks.

Pavel A Govyadinov, Tasha Womack, Jason L Eriksen, Guoning Chen, David Mayerich

Abstract read
In one paragraph

Article in IEEE transactions on visualization and computer graphics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pavel A Govyadinov
Tasha Womack
Jason L Eriksen
Guoning Chen
David Mayerich

Funding

Large-Scale Reconstruction of Microvascular Networks and the Surrounding CellularR00LM011390 · NLM · UNIVERSITY OF HOUSTON · PI MAYERICH, DAVID · 2014 to 2016
$730k
A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant MicrometastasesR21CA214299 · NCI · UNIVERSITY OF DELAWARE · PI SLATER, JOHN HUNDLEY · 2017 to 2019
$588k
NCI NIH HHS R21 CA214299NLM NIH HHS R00 LM011390
6 · The paper itself

Abstract

Advances in high-throughput imaging allow researchers to collect three-dimensional images of whole organ microvascular networks. These extremely large images contain networks that are highly complex, time consuming to segment, and difficult to visualize. In this paper, we present a framework for segmenting and visualizing vascular networks from terabyte-sized three-dimensional images collected using high-throughput microscopy. While these images require terabytes of storage, the volume devoted to the fiber network is ≈ 4 percent of the total volume size. While the networks themselves are sparse, they are tremendously complex, interconnected, and vary widely in diameter. We describe a parallel GPU-based predictor-corrector method for tracing filaments that is robust to noise and sampling errors common in these data sets. We also propose a number of visualization techniques designed to convey the complex statistical descriptions of fibers across large tissue sections-including commonly studied microvascular characteristics, such as orientation and volume.

Indexed as

AlgorithmsAnimalsBrainComputer GraphicsImaging, Three-DimensionalMiceMicroscopyMicrovessels

Identifiers

PMID29993636
PMCPMC6360128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.