ArticleIEEE transactions on bio-medical engineering2019
Noninvasive Magnetogastrography Detects Erythromycin-Induced Effects on the Gastric Slow Wave.
Article in IEEE transactions on bio-medical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- Pharmaceutical prokinetic and surgical interventions have opposing effects on gastroduodenal electromechanical coupling.Acta physiologica (Oxford, England) · 2025Article
- Noninvasive Quantification of Nausea Severity in Pediatric Functional Nausea.Gastro hep advances · 2025Article
- Stomach Geometry Reconstruction Using Serosal Transmitting Coils and Magnetic Source Localization.IEEE transactions on bio-medical engineering · 2023Article
- Multichannel magnetogastrogram: a clinical marker for pediatric chronic nausea.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Clinical application and research progress of extracellular slow wave recording in the gastrointestinal tract.World journal of gastrointestinal surgery · 2022Review
- The effect of chronic nausea on gastric slow wave spatiotemporal dynamics in children.Neurogastroenterology and motility · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveThe prokinetic action of erythromycin is clinically useful under conditions associated with gastrointestinal hypomotility. Although erythromycin is known to affect the electrogastrogram, no studies have examined the effects that erythromycin has on gastric slow wave magnetic fields.
methodsIn this study, gastric slow wave activity was assessed simultaneously using noninvasive magnetogastrogram (MGG), electrogastrogram, and mucosal electromyogram recordings. Recordings were obtained for 30 min prior to and 60 min after intravenous administration of erythromycin at dosages of 3 and 6 mg/kg.
resultsMGG recordings showed significant changes in the percentage power distribution of gastric signal after infusion of both 3 and 6 mg/kg erythromycin at t = 1-5 min that persisted for t = 30-40 min after infusion. These changes agree with the changes observed in the electromyogram. We did not observe any statistically significant difference in MGG amplitude before or after injection of either 3 or 6 mg/kg erythromycin. Both 3 and 6 mg/kg erythromycin infusion showed retrograde propagation with a statistically significant decrease in slow wave propagation velocity 11-20 min after infusion. Propagation velocity started returning toward baseline values after approximately 21-30 min for the 3 mg/kg dosage and after 31-40 min for a dosage of 6 mg/kg.
conclusionOur results showed that the magnetic signatures were sensitive to disruptions in normal slow wave activity induced by pharmacological and prokinetic agents such as erythromycin. SIGNIFICANCE: This study shows that repeatable noninvasive bio-electro-magnetic techniques can objectively characterize gastric dysrhythmias and may quantify treatment efficacy in patients with functional gastric disorders.
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Registered trials
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