Evidence map›Paper›PMID 29993445›Full record

ArticleIEEE transactions on bio-medical engineering2018

Medical Image Synthesis with Deep Convolutional Adversarial Networks.

Dong Nie, Roger Trullo, Jun Lian, Li Wang, Caroline Petitjean, Su Ruan, Qian Wang, Dinggang Shen

Erratum issuedAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed.

  1. Article
  2. Article
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  4. [A vessel-enhanced consistency-preserving diffusion model for 3T-to-7T susceptibility weighted image generation].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  12. [Cross modal translation of magnetic resonance imaging and computed tomography images based on diffusion generative adversarial networks].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Artificial intelligence in musculoskeletal applications: a primer for radiologists.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Review

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Dong Nie
Roger Trullo
Jun Lian
Li Wang
Caroline Petitjean
Su Ruan
Qian Wang
Dinggang Shen

Funding

Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
Automatic Pelvic Organ Delineation in Prostate Cancer TreatmentR01CA206100 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIAN, JUN · 2016 to 2022
$1.7M
NCI NIH HHS R01 CA206100NIBIB NIH HHS R01 EB006733
6 · The paper itself

Abstract

Medical imaging plays a critical role in various clinical applications. However, due to multiple considerations such as cost and radiation dose, the acquisition of certain image modalities may be limited. Thus, medical image synthesis can be of great benefit by estimating a desired imaging modality without incurring an actual scan. In this paper, we propose a generative adversarial approach to address this challenging problem. Specifically, we train a fully convolutional network (FCN) to generate a target image given a source image. To better model a nonlinear mapping from source to target and to produce more realistic target images, we propose to use the adversarial learning strategy to better model the FCN. Moreover, the FCN is designed to incorporate an image-gradient-difference-based loss function to avoid generating blurry target images. Long-term residual unit is also explored to help the training of the network. We further apply Auto-Context Model to implement a context-aware deep convolutional adversarial network. Experimental results show that our method is accurate and robust for synthesizing target images from the corresponding source images. In particular, we evaluate our method on three datasets, to address the tasks of generating CT from MRI and generating 7T MRI from 3T MRI images. Our method outperforms the state-of-the-art methods under comparison in all datasets and tasks.

Indexed as

Deep LearningBrainHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPelvisTomography, X-Ray Computed

Identifiers

PMID29993445
PMCPMC6398343

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.