ArticleScientific reports2018
Osteogenic Differentiation of Human Mesenchymal Stem cells in a 3D Woven Scaffold.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Bone Organoids as Advanced Models for Osteoporosis: Development, Application, and Future Prospects.International journal of molecular sciences · 2026Review
- Enhancement of bone healing through the direct injection of osteogenic and maintenance media concurrent with hydroxyapatite in a rat model of radial bone defects.Iranian journal of veterinary research · 2026Article
- In Vivo Cell Migration and Growth Within Electrospun Porous Nanofibrous Scaffolds with Different Pore Sizes in a Mouse Pouch Model.Journal of functional biomaterials · 2025Article
- The impact of graphene quantum dots on osteogenesis potential of Wharton's jelly mesenchymal stem cells in fibrin hydrogel scaffolds.Cytotechnology · 2025Article
- The order of green and red LEDs irradiation affects the neural differentiation of human umbilical cord matrix-derived mesenchymal cells.Scientific reports · 2024Article
- Synergistic effects of biological stimuli and flexion induce microcavities promote hypertrophy and inhibit chondrogenesis during in vitro culture of human mesenchymal stem cell aggregates.Biotechnology journal · 2024Article
- Direct Reprogramming of Fibroblasts to Osteoblasts: Techniques and Methodologies.Stem cells translational medicine · 2024Review
- GelMA/TCP nanocomposite scaffold for vital pulp therapy.Acta biomaterialia · 2024Article
- NOVEL HIGH-STRENGTH POLYESTER COMPOSITE SCAFFOLDS FOR BONE REGENERATION.Polymers for advanced technologies · 2023Article
- Osteogenic Potential of Human Dental Pulp Stem Cells (hDPSCs) Growing on Poly L-Lactide-Co-Caprolactone and Hyaluronic Acid (HYAFF-11International journal of molecular sciences · 2023Article
- Nanoscale β-TCP-Laden GelMA/PCL Composite Membrane for Guided Bone Regeneration.ACS applied materials & interfaces · 2023Article
- Enhanced Osteogenesis Potential of MG-63 Cells through Sustained Delivery of VEGF via Liposomal Hydrogel.Gels (Basel, Switzerland) · 2023Article
- Discussing the final size and shape of the reconstructed tissues in tissue engineering.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023Review
- From mesenchymal niches to engineeredMaterials today. Bio · 2022Article
- A collagen/PLA hybrid scaffold supports tendon-derived cell growth for tendon repair and regeneration.Journal of biomedical materials research. Part B, Applied biomaterials · 2022Article
- A Review of Woven Tracheal Stents: Materials, Structures, and Application.Journal of functional biomaterials · 2022Review
- Probing Notch1-Dll4 signaling in regulating osteogenic differentiation of human mesenchymal stem cells using single cell nanobiosensor.Scientific reports · 2022Article
- 3D Printed Poly(𝜀-caprolactone)/Hydroxyapatite Scaffolds for Bone Tissue Engineering: A Comparative Study on a Composite Preparation by Melt Blending or Solvent Casting Techniques and the Influence of Bioceramic Content on Scaffold Properties.International journal of molecular sciences · 2022Article
- Article
- Mesenchymal stem cells from biology to therapy.Emerging topics in life sciences · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fiber-based scaffolds produced by textile manufacturing technology offer versatile materials for tissue engineering applications since a wide range of crucial scaffold parameters, including porosity, pore size and interconnectivity, can be accurately controlled using 3D weaving. In this study, we developed a weavable, bioactive biodegradable composite fiber from poly (lactic acid) (PLA) and hydroxyapatite powder by melt spinning. Subsequently, scaffolds of these fibers were fabricated by 3D weaving. The differentiation of human mesenchymal stem cells (hMSCs) in vitro was studied on the 3D scaffolds and compared with differentiation on 2D substrates having the same material composition. Our data showed that the 3D woven scaffolds have a major impact on hMSCs proliferation and activation. The 3D architecture supports the differentiation of the hMSCs into osteoblast cells and enhances the production of mineralized bone matrix. The present study further confirms that a 3D scaffold promotes hMSCs differentiation into the osteoblast-lineage and bone mineralization.
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