Evidence map›Paper›PMID 29993026›Full record

ArticleScientific reports2018

Bridging the scales in high-throughput dielectrophoretic (bio-)particle separation in porous media.

Georg R Pesch, Malte Lorenz, Shaurya Sachdev, Samir Salameh, Fei Du, Michael Baune, Pouyan E Boukany, Jorg Thöming

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Georg R PeschUniversity of Bremen and Center for Environmental Research and Sustainable Technology, Chemical Engineering: Recovery and Recycling (VdW), Bremen, Germany. gpesch@uni-bremen.de.ORCID 0000-0003-4676-1908
Malte LorenzUniversity of Bremen and Center for Environmental Research and Sustainable Technology, Chemical Engineering: Recovery and Recycling (VdW), Bremen, Germany.
Shaurya SachdevDelft University of Technology, Department of Chemical Engineering, Delft, The Netherlands.
Samir SalamehDelft University of Technology, Department of Chemical Engineering, Delft, The Netherlands.
Fei DuUniversity of Bremen and Center for Environmental Research and Sustainable Technology, Chemical Engineering: Recovery and Recycling (VdW), Bremen, Germany.
Michael BauneUniversity of Bremen and Center for Environmental Research and Sustainable Technology, Chemical Engineering: Recovery and Recycling (VdW), Bremen, Germany.
Pouyan E BoukanyDelft University of Technology, Department of Chemical Engineering, Delft, The Netherlands. p.e.boukany@tudelft.nl.
Jorg ThömingUniversity of Bremen and Center for Environmental Research and Sustainable Technology, Chemical Engineering: Recovery and Recycling (VdW), Bremen, Germany.
University of Bremen · DEDelft University of Technology · NL

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) GRK 1860EC | Seventh Framework Programme (European Union Seventh Framework Programme) 337820
6 · The paper itself

Abstract

Dielectrophoresis (DEP) is a versatile technique for the solution of difficult (bio-)particle separation tasks based on size and material. Particle motion by DEP requires a highly inhomogeneous electric field. Thus, the throughput of classical DEP devices is limited by restrictions on the channel size to achieve large enough gradients. Here, we investigate dielectrophoretic filtration, in which channel size and separation performance are decoupled because particles are trapped at induced field maxima in a porous separation matrix. By simulating microfluidic model porous media, we derive design rules for DEP filters and verify them using model particles (polystyrene) and biological cells (S. cerevisiae, yeast). Further, we bridge the throughput gap by separating yeast in an alumina sponge and show that the design rules are equally applicable in real porous media at high throughput. While maintaining almost 100% efficiency, we process up to 9 mL min

Indexed as

Cell SeparationElectrophoresisLiquid BiopsyMicrofluidicsParticle SizePolystyrenesPorositySaccharomyces cerevisiaePolystyrenes

Identifiers

PMID29993026
PMCPMC6041321
OpenAlexW2853665590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.