ArticleInternational journal of cancer2019
Weight change since age 20 and incident risk of obesity-related cancer in Japan: a pooled analysis of the Miyagi Cohort Study and the Ohsaki Cohort Study.
Article in International journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Role of body mass index and weight change in the risk of cancer: A systematic review and meta-analysis of 66 cohort studies.Journal of global health · 2024Pooled it
- The association between CALLY index and obesity in adolescents: a comparative analysis with traditional inflammatory markers.Eating and weight disorders : EWD · 2026Article
- Sleeve gastrectomy protects lean mice from future obesity.bioRxiv : the preprint server for biology · 2026Article
- Sex and age differences in the association between obesity and long-term changes with the risk of incident type 2 diabetes mellitus: the Rural Deqing Cohort Study.Hepatobiliary surgery and nutrition · 2026Article
- Obesity, diabetes, and cancer: epidemiology, pathophysiology, and potential interventions.Archives of endocrinology and metabolism · 2023Review
- The Lifelong Health Support 10: a Japanese prescription for a long and healthy life.Environmental health and preventive medicine · 2022Review
- Higher Global Diet Quality Score Is Associated with Less 4-Year Weight Gain in US Women.The Journal of nutrition · 2021Article
- Body weight variability and cancer incidence in men aged 40 years and older-Korean National Insurance Service Cohort.Scientific reports · 2021Article
- Gender Differences in Obesity-Related Cancers.Current obesity reports · 2021Review
- Racial/ethnic differences in anthropometric and hormone-related factors and endometrial cancer risk: the Multiethnic Cohort Study.British journal of cancer · 2021Article
- Preventable fractions of cancer incidence attributable to 7-years weight gain in the Norwegian Women and Cancer (NOWAC) study.Scientific reports · 2021Article
- Levels of Physical Fitness and Weight Status in Children and Adolescents: A Comparison between China and Japan.International journal of environmental research and public health · 2020Article
- Mushroom consumption and incident risk of prostate cancer in Japan: A pooled analysis of the Miyagi Cohort Study and the Ohsaki Cohort Study.International journal of cancer · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is unclear whether weight change during adulthood affects the risk of obesity-related cancers such as those of the esophagus, colorectum, pancreas, breast, endometrium, and kidney among Japanese, where obesity is less frequent and less severe. We examined the association between weight change during adulthood and the risk of obesity-related cancer among Japanese by conducting a pooled analysis of two prospective studies of residents in Miyagi Prefecture, Japan. A total of 78,743 persons (40,422 women and 38,321 men) aged 40-79 years participated in the Miyagi Cohort Study in 1990 and in the Ohsaki Cohort Study in 1994. Weight change since age 20 was divided into four categories (weight loss; stable weight; moderate weight gain; high weight gain). Cox proportional hazards regression analysis was used to estimate the multivariate hazard ratios (HRs) and 95% confidence intervals (CIs) for obesity-related cancer incidence. During 1,057,899 person-years of follow up, 4,467 cases of obesity-related cancer (women; 1,916 cases, men; 2,551cases) were identified. In women, compared to the stable weight, weight gain was associated with an increased risk of obesity-related cancer (moderate weight gain; HRs = 1.10, 95%CIs: 0.97-1.26, high weight gain; HRs = 1.29, 95%CIs: 1.14-1.47). The results indicate that weight gain since age 20 was associated with a significantly increased risk of obesity-related cancer among Japanese women. By contrast, in men, our study found that weight change is not associated with the incidence of obesity-related cancer.
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