ArticleMolecular neurobiology2019
Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway.
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In one paragraph
Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Macrophage-associated kinase signaling in atherosclerosis - a systematic review.Cell communication and signaling : CCS · 2026Pooled it
- Advances in biomimetic mineralized biomaterials for bone tissue engineering.Regenerative biomaterials · 2026Review
- KLF7 Blocks MKNK2/HIF-1 Pathway-Mediated M1 Microglia Polarization to Ameliorate Ischemic Stroke-Induced Neurological Injury.Brain and behavior · 2025Article
- MicroRNAs modulate CaMKIIα/SIRT1 signaling pathway as a biomarker of cognitive ability in adolescents.Brain, behavior, & immunity - health · 2025Article
- [PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- CaeNeuro · 2024Article
- Calcium-Associated Proteins in Neuroregeneration.Biomolecules · 2024Review
- Ischemic Stroke and Autophagy: The Roles of Long Non-Coding RNAs.Current neuropharmacology · 2024Review
- Article
- The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Roles of lncRNAs in brain development and pathogenesis: Emerging therapeutic opportunities.Molecular therapy : the journal of the American Society of Gene Therapy · 2023Review
- Photobiomodulation improves the synapses and cognitive function and ameliorates epileptic seizure by inhibiting downregulation of Nlgn3.Cell & bioscience · 2023Article
- Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke.Bioengineered · 2022Review
- MiR-25 overexpression inhibits titanium particle-induced osteoclast differentiation via down-regulation of mitochondrial calcium uniporter in vitro.Journal of orthopaedic surgery and research · 2022Article
- Altered lncRNAs Transcriptomic Profiles in Atherosclerosis-Induced Ischemic Stroke.Cellular and molecular neurobiology · 2022Article
- The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1.Physiological reports · 2021Article
- Calcium/Calmodulin-Dependent Protein Kinase II in Cerebrovascular Diseases.Translational stroke research · 2021Review
- Article
- LncRNA SNHG15 Knockdown Protects Against OGD/R-Induced Neuron Injury by Downregulating TP53INP1 Expression via Binding to miR-455-3p.Neurochemical research · 2021Article
- circRNA CDR1as Promotes Pulmonary Artery Smooth Muscle Cell Calcification by Upregulating CAMK2D and CNN3 via Sponging miR-7-5p.Molecular therapy. Nucleic acids · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Jing YeDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA.
Sabyasachi DasDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA.
Adhiraj RoyDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA.
Wenzhong WeiDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Huachen HuangDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Joshua Michael Lorenz-GuertinDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA.
Qian XuChina-UK-NYNU-RRes Joint Laboratory, Nanyang Normal University, Nanyang, People's Republic of China.
Tija C JacobDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA.
Bing WangDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-9502-4851
Dandan SunDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Qiming Jane WangDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, E1354 BST, Pittsburgh, PA, 15261, USA. qjw1@pitt.edu.
University of Pittsburgh · USHarbin Medical University · CNNanyang Normal University · CN
Funding
Na-K-Cl Contransporter in Cerebral IschemiaR01NS038118 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SUN, DANDAN · 2000 to 2018
$5.0MPREDOCTORAL TRAINING IN PHARMACOLOGICAL SCIENCEST32GM008424 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PAGANO, PATRICK J · 1994 to 2019
$3.4MNovel long non-coding RNAs in neuronal survival in focal cerebral ischemiaR21NS096946 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, QIMING JANE · 2016 to 2017
$425kDiazepam induces synaptic GABA type A receptor plasticity via multiple trafficking mechanismsF31MH117839 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LORENZ-GUERTIN, JOSHUA · 2018 to 2019
$63kNIGMS NIH HHS T32 GM008424NIH HHS NS038118NIH HHS R21NS096946NIMH NIH HHS F31 MH117839NINDS NIH HHS R01 NS038118NINDS NIH HHS R21 NS096946U.S. Department of Defense PC150190
Abstract
Ca
Indexed as
AnimalsApoptosisBrainBrain IschemiaCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell LineCell SurvivalMiceNeuronsNeuroprotectionNF-kappa BRatsSignal TransductionUp-RegulationCalcium-Calmodulin-Dependent Protein Kinase Type 2NF-kappa BCaMKIIIn vitro ischemiaLong non-coding RNANeuroprotectionStroke
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.