Evidence map›Paper›PMID 29992526›Full record

ReviewCurrent hypertension reports2018

An Overview of Metabolic Phenotyping in Blood Pressure Research.

Ioanna Tzoulaki, Aikaterini Iliou, Emmanuel Mikros, Paul Elliott

Abstract readReview
In one paragraph

Review in Current hypertension reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Application of omics in hypertension and resistant hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Predicting response to lisinopril in treating hypertension: a pilot study.Metabolomics : Official journal of the Metabolomic Society · 2019
    Article
  20. Precision Medicine.Circulation research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ioanna TzoulakiDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. i.tzoulaki@imperial.ac.uk.
Aikaterini IliouDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Athens, Athens, Greece.
Emmanuel MikrosDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Athens, Athens, Greece.
Paul ElliottDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.

Funding

Department of Health HPRU-2012-10141Medical Research Council MR/L01341X/1Medical Research Council MR/L01632X/1
6 · The paper itself

Abstract

purpose of the reviewThis review presents the analytical techniques, processing and analytical steps used in metabolomics phenotyping studies, as well as the main results from epidemiological studies on the associations between metabolites and high blood pressure. RECENT

findingsA variety of metabolomic approaches have been applied to a range of epidemiological studies to uncover the pathophysiology of high blood pressure. Several pathways have been suggested in relation to blood pressure including the possible role of the gut microflora, inflammatory, oxidative stress, and lipid pathways. Metabolic changes have also been identified associated with blood pressure lowering effects of diets high in fruits and vegetables and low in meat intake. However, the current body of literature on metabolic profiling and blood pressure is still in its infancy, not fully consistent and requires careful interpretation. Metabolic phenotyping is a promising approach to uncover metabolic pathways associated with high blood pressure and throw light into the complex pathophysiology of hypertension.

Indexed as

MetabolomicsPhenotypeBiomedical ResearchBlood PressureDietEpidemiologic StudiesGastrointestinal MicrobiomeHumansBlood pressureEpidemiological studiesHypertensionMetabolic phenotypingMetabolomicsMicrobiome

Identifiers

PMID29992526
PMCPMC6061189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.