Evidence map›Paper›PMID 29992491›Full record

ArticleLasers in medical science2019

PBMT and topical diclofenac as single and combined treatment on skeletal muscle injury in diabetic rats: effects on biochemical and functional aspects.

Ligiane Souza Dos Santos, Joyce Camilla Saltorato, Marina Gaiato Monte, Rodrigo Labat Marcos, Rodrigo Álvaro Brandão Lopes-Martins, Shaiane Silva Tomazoni, Ernesto Cesar Pinto Leal-Junior, Rodrigo Leal de Paiva Carvalho

Open access · bronzeAbstract read
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In one paragraph

Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ligiane Souza Dos SantosMasters in Physical Therapy, Universidade do Sagrado Coração, Bauru, SP, Brazil.
Joyce Camilla SaltoratoMasters in Physical Therapy, Universidade do Sagrado Coração, Bauru, SP, Brazil.
Marina Gaiato MonteGraduation in Nutrition, Universidade do Sagrado Coração, Bauru, SP, Brazil.
Rodrigo Labat MarcosPostgraduate Program in Biophotonics Applied to Health Sciences, Nove de Julho University (UNINOVE), São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0147-0122
Rodrigo Álvaro Brandão Lopes-MartinsLaboratório de Biofotônica e Terapêutica Experimental, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos, SP, Brazil.
Shaiane Silva TomazoniMasters and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo (UNICID), São Paulo, SP, Brazil.
Ernesto Cesar Pinto Leal-JuniorLaboratory of Phototherapy in Sport and Exercise, Nove de Julho University (UNINOVE), São Paulo, SP, Brazil.
Rodrigo Leal de Paiva CarvalhoLaboratory of Physiology and Sport Performance (LAFIDE), School of Sciences, São Paulo State University - UNESP, Av. Eng. Luiz Edmundo C. Coube, Bauru, SP, 17033-360, Brazil. castorcarvalho@hotmail.com.
Universidade Sagrado Coração · BRUniversidade Nove de Julho · BRUniversidade Cidade de São Paulo · BRUniversidade do Vale do Paraíba · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise generates several benefits in a short time in patients with diabetes mellitus. However, it can increase the chances of muscle damage, a serious problem for diabetic patients. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat these injuries, despite the serious adverse effects. In this way, photobiomodulation therapy (PBMT) with low-level laser therapy (LLLT) and/or light emitting diode therapy (LEDT) can be used as an alternative in this case. However, its efficacy in tissue repair of trauma injuries in diabetes mellitus until now is unknown, as well as the combination between PBMT and NSAIDs. The objective of the present study was to evaluate the effects of NSAIDs and PBMT applied alone or combined on functional and biochemical aspects, in an experimental model of muscle injury through controlled trauma in diabetic rats. Muscle injury was induced by means of a single trauma to the animals' anterior tibialis muscle. After 1 h, the rats were treated with PBMT (830 nm; continuous mode, with a power output of 100 mW; 3.57 W/cm

Indexed as

Low-Level Light TherapyAdministration, TopicalAnimalsCombined Modality TherapyDiabetes Mellitus, ExperimentalDiclofenacDinoprostoneGene Expression RegulationMaleMuscle, SkeletalRats, WistarDiclofenacDinoprostoneDiabetes mellitusLow-level laser therapyPhotobiomodulation therapyRatsSkeletal muscle injuryTopical nonsteroidal anti-inflammatory drug

Identifiers

PMID29992491
OpenAlexW2832020208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.