ArticleBehavior research methods2019
Preprocessing pupil size data: Guidelines and code.
Article in Behavior research methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 1 of them a synthesis that pooled it.
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Who cites it
173 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review.Pflugers Archiv : European journal of physiology · 2023Pooled it
- Beware of What You Expect? A Partial Replication Study on the Behavioral and Psychophysiological Effects of Negative Expectations on Mechanical Hypersensitivity.Psychophysiology · 2026Trial
- Transcutaneous auricular vagus nerve stimulation during short-term motor practice drives cortical plasticity without behavioural improvement.The Journal of physiology · 2026Trial
- Vasopressin and angiotensin II pathways differentially modulate human fear response dynamics to looming threats.PLoS biology · 2026Trial
- Early intervention increases reactive joint attention in autistic preschoolers with arousal regulation as mediator.European child & adolescent psychiatry · 2025Trial
- The impact of doxycycline on human contextual fear memory.Psychopharmacology · 2024Trial
- Effect of the Matrix Metalloproteinase Inhibitor Doxycycline on Human Trace Fear Memory.eNeuro · 2023Trial
- Article
- Investigating the Effects of Paralinguistic Configuration in Background Human Speech on Attention: Protocol for a Within-Subject Study.JMIR research protocols · 2026Article
- Eye and Gaze Behavior During Human Disassembly Procedures: Effects of Task Conditions and Process Dynamics.Journal of eye movement research · 2026Article
- eyeris: A Flexible, Extensible, and Reproducible Pupillometry Preprocessing Framework in R.Psychophysiology · 2026Article
- Comparing feedback learning and arousal responses in Down, Fragile X, and Williams syndromes.NPJ science of learning · 2026Article
- gp3tools: An R Package for Reproducible Analysis and Reporting of Gazepoint GP3 Eye-Tracking Exports.Journal of eye movement research · 2026Article
- Article
- Classifying mental stress from eye tracking data: deep learning approaches for out-of-the-lab conditions.Scientific reports · 2026Article
- Windows to the goal: Pupillary working memory signatures prospectively adapt to task demands.iScience · 2026Article
- Trial-by-trial covariation of pupil dilation, microsaccades, and visual evoked potentials during saliency processing.iScience · 2026Article
- The Effect of Orthographic Neighbourhood and Semantics on Lexical Processing in a Transparent Orthographic Language: A Pupilometry Study.Journal of psycholinguistic research · 2026Article
- Unsupervised visual learning is revealed for task-irrelevant natural scenes due to reduced attentional suppression effects in visual areas.Nature communications · 2026Article
- Linking human brain functional connectivity to underlying neurotransmission.bioRxiv : the preprint server for biology · 2026Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pupillometry has been one of the most widely used response systems in psychophysiology. Changes in pupil size can reflect diverse cognitive and emotional states, ranging from arousal, interest and effort to social decisions, but they are also widely used in clinical practice to assess patients' brain functioning. As a result, research involving pupil size measurements has been reported in practically all psychology, psychiatry, and psychophysiological research journals, and now it has found its way into the primatology literature as well as into more practical applications, such as using pupil size as a measure of fatigue or a safety index during driving. The different systems used for recording pupil size are almost as variable as its applications, and all yield, as with many measurement techniques, a substantial amount of noise in addition to the real pupillometry data. Before analyzing pupil size, it is therefore of crucial importance first to detect this noise and deal with it appropriately, even prior to (if need be) resampling and baseline-correcting the data. In this article we first provide a short review of the literature on pupil size measurements, then we highlight the most important sources of noise and show how these can be detected. Finally, we provide step-by-step guidelines that will help those interested in pupil size to preprocess their data correctly. These guidelines are accompanied by an open source MATLAB script (available at https://github.com/ElioS-S/pupil-size ). Given that pupil diameter is easily measured by standard eyetracking technologies and can provide fundamental insights into cognitive and emotional processes, it is hoped that this article will further motivate scholars from different disciplines to study pupil size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.