Evidence map›Paper›PMID 29992184›Full record

ArticleInternational journal of cardiology. Heart & vasculature2018

Cardiovascular risk and mannose binding lectin in patients with rheumatoid arthritis from southern Brazil.

Barbara S Kahlow, Renato Nisihara, Roberta Petisco, Shirley R R Utiyama, Iara J Messias-Reason, Isabela Goeldner, Thelma L Skare

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Barbara S KahlowRheumatology Service, Evangelic University Hospital of Curitiba, Curitiba, PR, Brazil.
Renato NisiharaRheumatology Service, Evangelic University Hospital of Curitiba, Curitiba, PR, Brazil.
Roberta PetiscoRheumatology Service, Evangelic University Hospital of Curitiba, Curitiba, PR, Brazil.
Shirley R R UtiyamaDepartment of Clinical Analysis, Federal University of Paraná, Curitiba, PR, Brazil.
Iara J Messias-ReasonDepartment of Medical Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
Isabela GoeldnerDepartment of Medical Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
Thelma L SkareRheumatology Service, Evangelic University Hospital of Curitiba, Curitiba, PR, Brazil.
Hospital Universitário Evangélico de Curitiba · BRUniversidade Federal do Paraná · BRUniversidade Positivo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMannose binding lectin (MBL) appears to be involved in susceptibility to rheumatoid arthritis (RA), in the inflammatory process and in the genesis of atherosclerotic disease.

objectiveTo study the association of MBL serum levels and its genotypic variation with carotid arteries intimal thickness (IMT) in RA patients from Southern Brazil.

methodsMBL serum levels,

resultsA significant lower MBL serum concentration was observed in patients with RA in relation to controls (528 ng/mL vs 937.5 ng/mL,

conclusionRA patients had lower MBL levels than controls. MBL were negatively associated with CRP serum levels; low MBL genotypes producers increased thickness of the IMT than high producers.

Indexed as

AtherosclerosisMannose binding lectinRheumatoid arthritis

Identifiers

PMID29992184
PMCPMC6036938
OpenAlexW2862494162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.