Evidence map›Paper›PMID 29992163›Full record

ArticleBioMed research international2018

Composite Scaffolds Based on Intestinal Extracellular Matrices and Oxidized Polyvinyl Alcohol: A Preliminary Study for a New Regenerative Approach in Short Bowel Syndrome.

Francesca Grandi, Elena Stocco, Silvia Barbon, Anna Rambaldo, Martina Contran, Francesco Fascetti Leon, Piergiorgio Gamba, Pier Paolo Parnigotto, Veronica Macchi, Raffaele De Caro and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  16. Loss of Slfn3 induces a sex-dependent repair vulnerability after 50% bowel resection.American journal of physiology. Gastrointestinal and liver physiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Francesca GrandiDepartment of Women's and Children's Health, Pediatric Surgery, University of Padua, Via Giustiniani 3, 35121 Padua, Italy.
Elena StoccoSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.ORCID 0000-0003-4572-622X
Silvia BarbonFoundation for Biology and Regenerative Medicine, Tissue Engineering and Signaling (TES) ONLUS, Via De Sanctis 10, Caselle di Selvazzano Dentro, 35030 Padua, Italy.ORCID 0000-0003-2435-0753
Anna RambaldoSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.
Martina ContranSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.
Francesco Fascetti LeonDepartment of Women's and Children's Health, Pediatric Surgery, University of Padua, Via Giustiniani 3, 35121 Padua, Italy.
Piergiorgio GambaDepartment of Women's and Children's Health, Pediatric Surgery, University of Padua, Via Giustiniani 3, 35121 Padua, Italy.
Pier Paolo ParnigottoFoundation for Biology and Regenerative Medicine, Tissue Engineering and Signaling (TES) ONLUS, Via De Sanctis 10, Caselle di Selvazzano Dentro, 35030 Padua, Italy.
Veronica MacchiSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.
Raffaele De CaroSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.
Andrea PorzionatoSection of Human Anatomy, Department of Neurosciences, University of Padua, Via Gabelli 65, 35121 Padua, Italy.ORCID 0000-0003-3025-4717
University of Padua · ITFoundation for Cardiovascular Biomedical Research and Gene and Cell Therapy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric Short Bowel Syndrome is a rare malabsorption disease occurring because of massive surgical resections of the small intestine. To date, the issues related to current strategies including intestinal transplantation prompted the attention towards tissue engineering (TE). This work aimed to develop and compare two composite scaffolds for intestinal TE consisting of a novel hydrogel, that is, oxidized polyvinyl alcohol (OxPVA), cross-linked with decellularized intestinal wall as a whole (wW/OxPVA) or homogenized (hW/OxPVA). A characterization of the supports was performed by histology and Scanning Electron Microscopy and their interaction with adipose mesenchymal stem cells occurred by MTT assay. Finally, the scaffolds were implanted in the

Indexed as

Extracellular MatrixPolyvinyl AlcoholTissue EngineeringTissue ScaffoldsAnimalsChildHumansRatsRats, Sprague-DawleyShort Bowel SyndromePolyvinyl Alcohol

Identifiers

PMID29992163
PMCPMC5994320
OpenAlexW2804693185

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.