Evidence map›Paper›PMID 29992100›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2018

Rosa Maria Chura-Chambi, Tatiana Rodrigues Fraga, Ludmila Bezerra da Silva, Bruno Bernardi Yamamoto, Lourdes Isaac, Angela Silva Barbosa, Ligia Morganti

Open access · goldAbstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Leptolysin, aFrontiers in cellular and infection microbiology · 2022
    Article
  5. In Silico Structural and Functional Characterization of HtrA Proteins ofTropical medicine and infectious disease · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rosa Maria Chura-ChambiInstituto de Pesquisas Energéticas e Nucleares IPEN-CNEN/SP, Centro de Biotecnologia, Av. Prof. Lineu Prestes, 2242, CEP 05508-000, São Paulo, SP, Brazil.
Tatiana Rodrigues FragaInstituto de Ciências Biomédicas, Universidade de São Paulo, Departamento de Imunologia, Av. Prof. Lineu Prestes, 1374, CEP 05508-900, São Paulo, SP, Brazil.
Ludmila Bezerra da SilvaInstituto Butantan, Laboratório de Bacteriologia, Av. Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil.
Bruno Bernardi YamamotoInstituto Butantan, Laboratório de Bacteriologia, Av. Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil.
Lourdes IsaacInstituto de Ciências Biomédicas, Universidade de São Paulo, Departamento de Imunologia, Av. Prof. Lineu Prestes, 1374, CEP 05508-900, São Paulo, SP, Brazil.
Angela Silva BarbosaInstituto Butantan, Laboratório de Bacteriologia, Av. Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil.
Ligia MorgantiInstituto de Pesquisas Energéticas e Nucleares IPEN-CNEN/SP, Centro de Biotecnologia, Av. Prof. Lineu Prestes, 2242, CEP 05508-000, São Paulo, SP, Brazil.
Instituto Butantan · BRInstituto de Pesquisas Energéticas e Nucleares · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymes from the thermolysin family are crucial factors in the pathogenesis of several diseases caused by bacteria and are potential targets for therapeutic interventions. Thermolysin encoded by the gene LIC13322 of the causative agent of leptospirosis,

Indexed as

Alkaline pHGdnHCl, guanidine hydrochlorideHHP, high hydrostatic pressureHigh hydrostatic pressureIPTG, isopropyl β-D-thiogalactopyranosideLB, Luria-Bertani brothLS, light scatteringMetalloproteaseRefoldingSDS-PAGE, sodium dodecyl sulphate polyacrylamide gel electrophoresisSEC, size exclusion chromatographyThermolysinTL-IB, inclusion bodies of thermolysin

Identifiers

PMID29992100
PMCPMC6036645
OpenAlexW2808949903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.