Evidence map›Paper›PMID 29991990›Full record

ArticleEuropean journal of translational myology2018

Culture conditions influence satellite cell activation and survival of single myofibers.

Alessandra Renzini, Anna Benedetti, Marina Bouchè, Leopoldo Silvestroni, Sergio Adamo, Viviana Moresi

Abstract read
In one paragraph

Article in European journal of translational myology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Available In Vitro Models for Human Satellite Cells from Skeletal Muscle.International journal of molecular sciences · 2021
    Review
  7. Review
  8. Targeting PKCθ Promotes Satellite Cell Self-Renewal.International journal of molecular sciences · 2020
    Article
  9. Article
  10. EJTM3 is also covering Mobility and Medicine at large, an update.European journal of translational myology · 2018
    Article
  11. Implementing EjtMEuropean journal of translational myology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandra RenziniDAHFMO Unit of Histology and Medical Embryology, InterUniversity Institute of Myology, Sapienza University of Rome, Italy.
Anna BenedettiDAHFMO Unit of Histology and Medical Embryology, InterUniversity Institute of Myology, Sapienza University of Rome, Italy.
Marina BouchèDAHFMO Unit of Histology and Medical Embryology, InterUniversity Institute of Myology, Sapienza University of Rome, Italy.
Leopoldo SilvestroniDepartment of Fundamental and Basic Sciences for Engineering, Sapienza University of Rome, Italy.
Sergio AdamoDAHFMO Unit of Histology and Medical Embryology, InterUniversity Institute of Myology, Sapienza University of Rome, Italy.
Viviana MoresiDAHFMO Unit of Histology and Medical Embryology, InterUniversity Institute of Myology, Sapienza University of Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved. This technique is an indispensable tool by which the muscle regeneration process can be recapitulated and studied in each specific phase, from satellite cell activation to proliferation, from differentiation to fusion. This study aims to clarify the effect of different culture conditions on single myofibers, their associated satellite cells, and the physiological behavior of the satellite cells upon long term culture. By direct observations of the cultures, we compared different experimental conditions and their effect on both satellite cell behavior and myofiber viability.

Indexed as

cell adhesiongrowth factorsmyofibersproliferationquiescencesatellite cells

Identifiers

PMID29991990
PMCPMC6036316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.