Evidence map›Paper›PMID 29991744›Full record

ArticleCell death & disease2018

CCL5-deficiency enhances intratumoral infiltration of CD8

Shengbo Zhang, Ming Zhong, Chao Wang, Yanjie Xu, Wei-Qiang Gao, Yan Zhang

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
2.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. New insights on anti-tumor immunity of CD8Journal of translational medicine · 2025
    Review
  6. The role of CD8Heliyon · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Derivation of CD8iScience · 2023
    Article
  16. Review
  17. Review
  18. CD24Global medical genetics · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shengbo ZhangState Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Renji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030, Shanghai, China.
Ming ZhongDepartment of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 200127, Shanghai, China.
Chao WangState Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Renji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030, Shanghai, China.
Yanjie XuState Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Renji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030, Shanghai, China.
Wei-Qiang GaoState Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Renji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030, Shanghai, China. gao.weiqiang@sjtu.edu.cn.
Yan ZhangState Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Renji Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030, Shanghai, China. yanzh@sjtu.edu.cn.
Shanghai Jiao Tong University · CNState Key Laboratory of Oncogene and Related Genes · CN

Funding

Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2017YFA0102900National Natural Science Foundation of China (National Science Foundation of China) 81372257National Natural Science Foundation of China (National Science Foundation of China) 81630073Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission) 16JC1405700
6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most common solid tumor in the world and shows resistance to several immunotherapies, particularly immune checkpoint blockade which has therapeutic effects on many other types of cancer. Cytotoxic CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesChemokine CCL5Colorectal NeoplasmsFemaleHumansMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutNeutrophil InfiltrationPhylogenyTumor MicroenvironmentChemokine CCL5

Identifiers

PMID29991744
PMCPMC6039518
OpenAlexW2882007132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.