Evidence map›Paper›PMID 29991601›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA.

David G Welkie, Benjamin E Rubin, Yong-Gang Chang, Spencer Diamond, Scott A Rifkin, Andy LiWang, Susan S Golden

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
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  10. The inner workings of an ancient biological clock.Trends in biochemical sciences · 2024
    Review
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  20. Altered Carbon Partitioning Enhances COBiodesign research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David G WelkieCenter for Circadian Biology, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-0173-1457
Benjamin E RubinDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.
Yong-Gang ChangSchool of Natural Sciences, University of California, Merced, CA 95343.
Spencer DiamondDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.
Scott A RifkinDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0001-8476-3256
Andy LiWangCenter for Circadian Biology, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-4741-6946
Susan S GoldenCenter for Circadian Biology, University of California, San Diego, La Jolla, CA 92093; sgolden@ucsd.edu.ORCID 0000-0002-4264-7019
University of California San Diego · USUniversity of California, Merced · USPlanetary Science Institute · US

Funding

GENETIC MECHANISMS AND REGULATIONT32GM007240 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMPTON, RANDOLPH Y. · 1985 to 2019
$23.8M
Undergraduate Summer Research Experience: Molecular and cellular mechanisms of circadian timekeeping in a prokaryote modelR35GM118290 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2016 to 2025
$6.7M
The Linchpin that Joins the Circadian Oscillator to Clock OutputR01GM107521 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI LIWANG, ANDY · 2014 to 2021
$2.8M
NIGMS NIH HHS R01 GM107521NIGMS NIH HHS R35 GM118290NIGMS NIH HHS T32 GM007240
6 · The paper itself

Abstract

The recurrent pattern of light and darkness generated by Earth's axial rotation has profoundly influenced the evolution of organisms, selecting for both biological mechanisms that respond acutely to environmental changes and circadian clocks that program physiology in anticipation of daily variations. The necessity to integrate environmental responsiveness and circadian programming is exemplified in photosynthetic organisms such as cyanobacteria, which depend on light-driven photochemical processes. The cyanobacterium

Indexed as

Bacterial ProteinsCircadian Rhythm Signaling Peptides and ProteinsGenome-Wide Association StudySynechococcusCircadian ClocksPhotosynthesisSignal TransductionBacterial ProteinsCircadian Rhythm Signaling Peptides and ProteinsKaiA protein, cyanobacteriacircadian clockcyanobacteriadiurnal physiologyphotosynthesistransposon sequencing

Identifiers

PMID29991601
PMCPMC6064986
OpenAlexW2952115612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.