ArticleProceedings of the National Academy of Sciences of the United States of America2018
Oscillatory inertial focusing in infinite microchannels.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Microfluidic pulse oscillator enabled by a shapeshifting liquid metal capacitor.Nature communications · 2026Article
- Article
- A Pump-Free, Hydraulic-Amplification Oscillatory Microfluidic Device for Continuous Particle and Cell Manipulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- High-efficient white blood cell separation from whole blood using cascaded inertial microfluidics.Talanta · 2025Article
- Microfluidic Nanoparticle Separation for Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- Capillary wave tweezer.Scientific reports · 2024Article
- Synchronous oscillatory electro-inertial focusing of microparticles.Biomicrofluidics · 2023Article
- Sheathless inertial particle focusing methods within microfluidic devices: a review.Frontiers in bioengineering and biotechnology · 2023Review
- Platelet-Derived Exosomes and Atherothrombosis.Frontiers in cardiovascular medicine · 2022Review
- Length-based separation ofMicrosystems & nanoengineering · 2022Article
- Neutrally Buoyant Particle Migration in Poiseuille Flow Driven by Pulsatile Velocity.Micromachines · 2021Article
- High-resolution particle separation by inertial focusing in high aspect ratio curved microfluidics.Scientific reports · 2021Article
- On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms.Sensors (Basel, Switzerland) · 2021Article
- Numerical Investigation of T-Shaped Microfluidic Oscillator with Viscoelastic Fluid.Micromachines · 2021Article
- High throughput viscoelastic particle focusing and separation in spiral microchannels.Scientific reports · 2021Article
- AC Insulator-Based Dielectrophoretic Focusing of Particles and Cells in an "Infinite" Microchannel.Analytical chemistry · 2021Article
- Resolving dynamics of inertial migration in straight and curved microchannels by direct cross-sectional imaging.Biomicrofluidics · 2021Article
- In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics.Lab on a chip · 2020Article
- A Review of Secondary Flow in Inertial Microfluidics.Micromachines · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Inertial microfluidics (i.e., migration and focusing of particles in finite Reynolds number microchannel flows) is a passive, precise, and high-throughput method for microparticle manipulation and sorting. Therefore, it has been utilized in numerous biomedical applications including phenotypic cell screening, blood fractionation, and rare-cell isolation. Nonetheless, the applications of this technology have been limited to larger bioparticles such as blood cells, circulating tumor cells, and stem cells, because smaller particles require drastically longer channels for inertial focusing, which increases the pressure requirement and the footprint of the device to the extent that the system becomes unfeasible. Inertial manipulation of smaller bioparticles such as fungi, bacteria, viruses, and other pathogens or blood components such as platelets and exosomes is of significant interest. Here, we show that using oscillatory microfluidics, inertial focusing in practically "infinite channels" can be achieved, allowing for focusing of micron-scale (i.e. hundreds of nanometers) particles. This method enables manipulation of particles at extremely low particle Reynolds number (
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