Evidence map›Paper›PMID 29991587›Full record

ArticlemBio2018

cAMP Receptor Protein Controls Vibrio cholerae Gene Expression in Response to Host Colonization.

Jainaba Manneh-Roussel, James R J Haycocks, Andrés Magán, Nicolas Perez-Soto, Kerstin Voelz, Andrew Camilli, Anne-Marie Krachler, David C Grainger

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Actuation of CRP activating region 3 by formylation modulates theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Cholera for travellers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Article
  6. A 3'UTR-derived small RNA modulates the life cycle of the cholera toxin-encoding filamentous phage, CTXϕ.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Review
  9. Sugar Import SuppressesbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Non-O1/Non-O139Microorganisms · 2024
    Review
  15. The cAMP Receptor Protein (CRP) ofAnimals : an open access journal from MDPI · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jainaba Manneh-Roussel *Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
James R J Haycocks *Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Andrés MagánInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Nicolas Perez-SotoInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Kerstin VoelzInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Andrew CamilliDepartment of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, USA.
Anne-Marie KrachlerInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
David C GraingerInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom d.grainger@bham.ac.uk.
University of Birmingham · GBHoward Hughes Medical Institute · USThe University of Texas Health Science Center at Houston · US

Funding

Study of transmissible forms of Vibrio CholeraeR01AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI CAMILLI, ANDREW · 2003 to 2019
$5.8M
Mechanoregulation of EHEC virulenceR01AI132354 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Anne-Marie Krachler · 2018 to 2026
$3.5M
Phage Resistance in Emergent Vibrio cholerae and Phage Prophylaxis of CholeraR37AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI Andrew Camilli · 2020 to 2026
$3.4M
Biotechnology and Biological Sciences Research Council BB/N005961/1Howard Hughes Medical InstituteNIAID NIH HHS R01 AI055058NIAID NIH HHS R01 AI132354NIAID NIH HHS R37 AI055058
6 · The paper itself

Abstract

The bacterium

Indexed as

Gene Expression Regulation, BacterialCyclic AMP Receptor ProteinDNA-Directed RNA PolymerasesProtein BindingVibrio choleraeCyclic AMP Receptor ProteinDNA-Directed RNA Polymerasesbiochemistrygene regulationgenome analysisVibrio

Identifiers

PMID29991587
PMCPMC6050953
OpenAlexW2830729077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.