ArticleBMJ case reports2018
Cold agglutinin-mediated autoimmune haemolytic anaemia associated with diffuse large B cell lymphoma.
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Clinical characterization and targeted genetic mutation profiling of autoimmune disease-associated B-cell lymphoma.Discover oncology · 2026Article
- Intervascular Large B-cell Lymphoma with Severe Anemia and a High-titer of Cold Agglutinin.Internal medicine (Tokyo, Japan) · 2025Article
- A Case of Primary Cold Agglutinin-Mediated Hemolytic Anemia Successfully Treated with Steroids.Cureus · 2025Article
- Low-grade B cell lymphoma in the perirenal space of the left kidney associated with high titer cold agglutinin disease.American journal of blood research · 2023Article
- COVID-19 and Cold Agglutinin Hemolytic Anemia.TH open : companion journal to thrombosis and haemostasis · 2020Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cold agglutinin-mediated autoimmune haemolytic anaemia is associated with the development of autoantibodies that can agglutinate red blood cells at cold temperatures. While primary cold agglutinin disease is an idiopathic lymphoproliferative disorder, secondary cold agglutinin syndrome (CAS) complicates other diseases such as infections, autoimmune diseases and cancers, mostly low-grade lymphomas. Early recognition, treatment of CAS and treatment of its associated underlying diseases are crucial to a successful outcome. We report a case of CAS in a setting of diffuse large B cell lymphoma, in which the treatment course was complicated by worsened anaemia due to chemotherapy-induced myelosuppression. We reviewed previously reported cases and discussed diagnosis and treatment strategies, including novel complement inhibitors, as potential future therapy.
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