ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018
Severe Chronic Abuse of Zolpidem in Refractory Insomnia.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats.Fundamental & clinical pharmacology · 2026Article
- Adverse event reports of seizure for insomnia medication from 1967 to 2023.Scientific reports · 2025Article
- Zolpidem-triggered atrial fibrillation in a patient with cardiomyopathy: a case report.BMC cardiovascular disorders · 2024Article
- Abusive use of Zolpidem as a Result of COVID-19 and Perspectives of Continuity of the Problem in the Post-Pandemic Period.Current neuropharmacology · 2024Review
- Case report: Additional grounds for tighter regulation? A case series of five women with zolpidem dependence from a Brazilian women-specific substance use disorder outpatient service.Frontiers in psychiatry · 2024Article
- 2023 Guidelines on the Diagnosis and Treatment of Insomnia in Adults - Brazilian Sleep Association.Sleep science (Sao Paulo, Brazil) · 2023Review
- Electrophysiological and Neuropsychological Indices of Cognitive Dysfunction in Patients with Chronic Insomnia and Severe Benzodiazepine Use Disorder.Brain sciences · 2023Article
- Severe chronic abuse of zolpidem for over 10 years: a case report and review of similar cases.Frontiers in psychiatry · 2023Article
- Case report: Chronological symptom profile after cessation of overdose zolpidem in a patient with comorbid bipolar disorder-from anxiety, craving, paresthesia and influenza-like symptoms to seizures and hallucinations.Frontiers in psychiatry · 2022Article
- Regulatory Framework Implementation for the Prescription of Zolpidem in France, What Impact in the Older People?International journal of environmental research and public health · 2021Observational
- 'Z-trip'? A Comprehensive Overview and a Case-series of Zolpidem Misuse.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021Article
- Zolpidem: Efficacy and Side Effects for Insomnia.Health psychology research · 2021Review
- The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy.Current neuropharmacology · 2021Review
- Zolpidem withdrawal seizure in an Iranian young woman: A case presentation.Caspian journal of internal medicine · 2021Article
- Consequences of the new zolpidem prescription regulations: a cohort study from the French national healthcare database.European journal of clinical pharmacology · 2020Article
- An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions.The international journal of neuropsychopharmacology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractZolpidem is an imidazopyridine nonbenzodiazepine hypnotic drug with a high affinity to the α1 subunit of the gamma amino butyric acid A receptor It is the first pharmacological option in the short-term management of sleep-onset insomnia. Initially considered a safer drug compared to benzodiazepines because of lower liability for abuse and dependence, recently, an increasing body of reports has questioned zolpidem's proneness to misuse. In this report, we describe a case of serious zolpidem abuse requiring pharmacological washout during hospitalization because of previous withdrawal seizures in a patient with chronic sleep-onset and maintenance insomnia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.