ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018
Craniofacial Phenotyping in Chinese and Caucasian Patients With Sleep Apnea: Influence of Ethnicity and Sex.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Two-dimensional facial photography for assessment of craniofacial morphology in sleep breathing disorders: a systematic review.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Sex differences in sleep architecture and nocturnal oxygenation across obstructive sleep apnea severity: an observational hospital-based study.Biology of sex differences · 2026Observational
- Cardiovascular Disease, Sleep-Disordered Breathing, and Artificial Intelligence: From Neutral Trials to Precision Sleep Cardiology.Reviews in cardiovascular medicine · 2026Review
- Lingual frenulum, craniofacial morphology, and obstructive sleep apnea: a mediation analysis.Sleep & breathing = Schlaf & Atmung · 2026Article
- Is Maxillomandibular Advancement Possible in Skeletal Class III Patients? A Scoping Review.Journal of clinical medicine · 2026Review
- Craniofacial photography for detection of positional obstructive sleep apnoea.Sleep and biological rhythms · 2026Article
- Prevalence and treatments of Sleep-Disordered breathing in people with down syndrome: A narrative review.Sleep & breathing = Schlaf & Atmung · 2025Review
- Surgical Management of Pediatric Obstructive Sleep Apnea: Efficacy, Outcomes, and Alternatives-A Systematic Review.Life (Basel, Switzerland) · 2024Review
- Cheeks appearance as a novel predictor of obstructive sleep apnea: the CASA score study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Observational
- Elucidating the association of obstructive sleep apnea with brain structure and cognitive performance.BMC psychiatry · 2024Article
- Self-helped detection of obstructive sleep apnea based on automated facial recognition and machine learning.Sleep & breathing = Schlaf & Atmung · 2023Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Causal associations between obstructive sleep apnea and COVID-19: A bidirectional Mendelian randomization study.Sleep medicine · 2023Article
- Clinical Characteristics Combined with Craniofacial Photographic Analysis in Children with Obstructive Sleep Apnea.Nature and science of sleep · 2023Article
- Mediating Effect of Self-Cognitive Oral Health Status on the Effect of Obstructive Sleep Apnea Risk Factors on Quality of Life (HINT-8) in Middle-Aged Korean Women: The Korea National Health and Nutrition Examination Survey.Life (Basel, Switzerland) · 2022Article
- Sleep apnea and recurrent heart failure hospitalizations after coronary artery bypass grafting.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Craniofacial photography and association with sleep-disordered breathing severity in children.Sleep & breathing = Schlaf & Atmung · 2020Article
- Evaluation of stylohyoid complex in subjects with different types of malocclusions using cone-beam computed tomography: a retrospective study in a Turkish subpopulation.Surgical and radiologic anatomy : SRA · 2020Article
- Predicting sleep apnea from three-dimensional face photography.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesCraniofacial abnormalities are a risk factor for obstructive sleep apnea (OSA). We have previously shown that phenotypic information derived from craniofacial photographs predict OSA in sleep clinic populations. However, there are likely ethnic and sex differences in craniofacial phenotypes related to OSA. We aimed to assess the use of craniofacial photography to identify interactions between OSA, ethnicity, and sex in craniofacial phenotype.
methodsFrontal and profile craniofacial photographs were analyzed from two sleep clinic populations of different ethnicity (Hong Kong Chinese, Australian Caucasians). OSA was defined as apnea-hypopnea index (AHI) > 10 events/h. Ten craniofacial measurements (three angles relating to jaw position and seven ratios describing proportions of the face) were examined for interactions between OSA status and sex or ethnicity) using factorial analysis of variance.
resultsA total of 363 subjects (25% female) were included (n = 200 Chinese, n = 163 Caucasian), of which 33% were controls. There were two-way interactions for OSA with both sex (mandibular plane angle [
conclusionsWe provide evidence of ethnic and sex differences in facial phenotype related to OSA. Furthermore, we demonstrate that craniofacial photography can be used as a phenotypic tool to assess these differences and allow investigation of OSA phenotypes in large samples. This has relevance to personalizing OSA recognition strategies across different populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.