Evidence map›Paper›PMID 29991422›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Adropin and Inflammation Biomarker Levels in Male Patients With Obstructive Sleep Apnea: A Link With Glucose Metabolism and Sleep Parameters.

Josko Bozic, Josip A Borovac, Tea Galic, Tina Ticinovic Kurir, Daniela Supe-Domic, Zoran Dogas

Abstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  17. SARS-CoV-2 Infection and Candidate Biomarkers.The Eurasian journal of medicine · 2022
    Article
  18. Article
  19. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Josko BozicDepartment of Pathophysiology, University of Split School of Medicine, Split, Croatia.
Josip A BorovacDepartment of Pathophysiology, University of Split School of Medicine, Split, Croatia.
Tea GalicDepartment of Neuroscience, University of Split School of Medicine, Split, Croatia.
Tina Ticinovic KurirDepartment of Pathophysiology, University of Split School of Medicine, Split, Croatia.
Daniela Supe-DomicDepartment of Medical Laboratory Diagnostics, University Hospital of Split, Split, Croatia.
Zoran DogasDepartment of Neuroscience, University of Split School of Medicine, Split, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesThe main objectives of the study were to determine plasma adropin, systemic inflammation biomarker levels, and glucose metabolism parameters in patients with moderate and severe obstructive sleep apnea (OSA) compared to healthy controls.

methodsIn this study, we included 50 male patients with OSA (25 moderate and 25 severe) and 25 age- and sex-matched control subjects. All subjects underwent fasting sampling of peripheral blood for laboratory analyses.

resultsAdropin plasma levels were significantly lower in the severe OSA group in comparison with the moderate and control groups (4.50 ± 1.45 versus 6.55 ± 1.68 versus 8.15 ± 1.79 ng/mL,

conclusionsPlasma adropin concentrations significantly correlate with indices of disease severity in patients with OSA, suggesting that adropin potentially plays an important role in the complex pathophysiology of the disease.

Indexed as

BiomarkersBlood GlucoseHumansInflammationMaleMiddle AgedPeptide HormonesSeverity of Illness IndexSleep Apnea, ObstructiveBiomarkersBlood GlucosePeptide Hormonesadropininflammation mediatorsmetabolismobstructive sleep apneapolysomnography

Identifiers

PMID29991422
PMCPMC6040799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.