Evidence map›Paper›PMID 29991366›Full record

SynthesisEpidemiology and infection2018

Amoebiasis in Iran: a systematic review and meta-analysis.

Ali Haghighi, Seyed Mohammad Riahi, Ali Taghipour, Adel Spotin, Mostafa Javanian, Mohsen Mohammadi, Mohammadreza Esmaeili Dooki, Ali Rostami

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Molecular identification ofVeterinary world · 2024
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  8. Frequency ofJournal of parasitology research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali HaghighiDepartment of Parasitology and Mycology,School of Medicine,Shahid Beheshti University of Medical Science,Tehran,Iran.
Seyed Mohammad RiahiDepartment of Epidemiology,School of Public Health, Student's committee research,Shahid Beheshti University of Medical Sciences,Tehran,Iran.
Ali TaghipourDepartment of Parasitology and Mycology,School of Medicine,Shahid Beheshti University of Medical Science,Tehran,Iran.
Adel SpotinInfectious and Tropical Diseases Research Center,Tabriz University of Medical Sciences,Tabriz,Iran.
Mostafa JavanianInfectious Diseases and Tropical Medicine Research Center,Health Research Institute,Babol University of Medical Sciences,Babol,I.R. Iran.
Mohsen MohammadiNon-Communicable Pediatric Diseases Research Center,Health Research Institute,Babol University of Medical Sciences,Babol,I.R. Iran.
Mohammadreza Esmaeili DookiNon-Communicable Pediatric Diseases Research Center,Health Research Institute,Babol University of Medical Sciences,Babol,I.R. Iran.
Ali RostamiInfectious Diseases and Tropical Medicine Research Center,Health Research Institute,Babol University of Medical Sciences,Babol,I.R. Iran.ORCID 0000-0002-1358-1321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A comprehensive meta-analysis study was performed to estimate the reliable national prevalence and molecular epidemiology of amoebiasis in Iran. Nine English and Persian databases were searched to achieve the relevant studies. Pooled estimates were generated and meta-regression was performed. We identified 71 eligible articles involving 330 930 subjects from 25 provinces to be included in the final analysis. Moreover, 17 studies compromising 462 polymerase chain reaction (PCR)-positive isolates performed molecular analysis to inter-species differentiation. The pooled prevalence of Entamoeba infection among Iranian population was about 1% (95% CI 0.8-2.0%). Moreover, regarding Human Development Index (HDI), a higher prevalence was observed in undeveloped provinces. Out of 462 PCR-positive isolates, 83% (95% CI 69-94%) and 12% (95% CI 3-24%) were Entamoeba dispar, Entamoeba histolytica, respectively. In subgroup analysis based on molecular results, in general, population prevalence of Entamoeba dispar and E. histolytica were 91% (95% CI 80-99%) and 7%, (95% CI 0-19%), respectively, while prevalence of these species in patients with gastrointestinal disorders were 75% (95% CI 45-96%) and 18% (95% CI 1-43%), respectively. Our findings indicate the low burden of amoebiasis in Iran. E. dispar, that is mostly non-pathogenic, was identified as most prevalent species. Nevertheless, we suggest more public health interventions in areas with lower HDI.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolEntamoeba histolyticaEntamoebiasisFemaleHumansInfantInfant, NewbornIranMaleMiddle AgedMolecular EpidemiologyAmoebiasisIranmeta-analysismolecular epidemiologyprevalence

Identifiers

PMID29991366
PMCPMC6452996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.