Evidence map›Paper›PMID 29991280›Full record

ArticleCell transplantation2018

Characteristics of Female Germline Stem Cells from Porcine Ovaries at Sexual Maturity.

Lin Hou, Jian Wang, Xinyue Li, Hu Wang, Guishu Liu, Bo Xu, Xingxing Mei, Xiuguo Hua, Ji Wu

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Oogonial stem cells: the unexpected superheroes.Reproduction & fertility · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Female germline stem cells: aging and anti-aging.Journal of ovarian research · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Comparison of RNA mMolecular therapy. Nucleic acids · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Role of stem cells in fertility preservation: current insights.Stem cells and cloning : advances and applications · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lin Hou1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Jian Wang1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Xinyue Li1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Hu Wang1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Guishu Liu2 The First People's Hospital of Chenzhou, Chenzhou, Hunan, China.
Bo Xu1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Xingxing Mei1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Xiuguo Hua3 Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Ji Wu1 Key Laboratory for the Genetics of Developmental, Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Jiao Tong University · CNChenzhou First People's Hospital · CNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigs share many anatomical and physiological features with humans, offering a unique and viable model for biomedical research. Although porcine female germline stem cells (FGSCs) were identified in the juvenile ovary, no reports described the isolation and purification of FGSCs from the pig at sexual maturity. Here, we isolated, purified, and cultured FGSCs from porcine ovaries at sexual maturity. Furthermore, we established and characterized the porcine FGSC (pFGSC) lines. In addition, we found that pFGSC lines could differentiate into oocytes when injection into tissue grafts, including human ovarian tissues. The results show that FGSCs exist in ovaries of Banna mini-pigs at juvenile and sexually maturity. These findings have implications in animal biotechnology applications and regeneration medicine.

Indexed as

Sexual MaturationAnimalsCell DifferentiationCells, CulturedCell SeparationFemaleOocytesOogenesisOogonial Stem CellsOvarySwineSwine, Miniaturefemale germline stem cellovarypigsexual maturity

Identifiers

PMID29991280
PMCPMC6434470
OpenAlexW2847305864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.