Evidence map›Paper›PMID 29990316›Full record

ArticlePloS one2018

Schiff bases containing a furoxan moiety as potential nitric oxide donors in plant tissues.

Emilian Georgescu, Anca Oancea, Florentina Georgescu, Alina Nicolescu, Elena Iulia Oprita, Lucian Vladulescu, Marius-Constantin Vladulescu, Florin Oancea, Sergiu Shova, Calin Deleanu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Emilian GeorgescuResearch Center Oltchim, RamnicuValcea, Romania.
Anca OanceaNational Institute of Research and Development for Biological Sciences, Bucharest, Romania.
Florentina GeorgescuResearch Dept., Teso Spec S.R.L., Fundulea, Calarasi, Romania.
Alina Nicolescu"PetruPoni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda, Iasi, Romania.
Elena Iulia OpritaNational Institute of Research and Development for Biological Sciences, Bucharest, Romania.
Lucian VladulescuResearch Dept., Teso Spec S.R.L., Fundulea, Calarasi, Romania.
Marius-Constantin VladulescuResearch Dept., Teso Spec S.R.L., Fundulea, Calarasi, Romania.
Florin OanceaNational Research & Development Institute for Chemistry & Petrochemistry - ICECHIM, Bucharest, Romania.
Sergiu Shova"PetruPoni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda, Iasi, Romania.
Calin Deleanu"PetruPoni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda, Iasi, Romania.ORCID 0000-0001-8206-5227
Institutul de Cercetari Electrotehnice · RONational Institute of Research and Development for Biological Sciences · RORomanian Academy · ROAcademy of Sciences of Moldova · MDNational Institute for Research and Development in Informatics - ICI Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stable Schiff bases containing a furoxan moiety are synthesized as single regioisomers by the reaction of 3-methyl-2-oxy-furazan-4-carbaldehydewith various amino compounds at room temperature. The structures of synthesized compounds were fully characterized by multinuclear NMR spectroscopy and X-ray crystallography. The effect of synthesized Schiff bases containing a furoxan moiety on biological generation of reactive oxygen species and nitric oxide in plant tissues was investigated for the first time by fluorescence microscopy and the released NO identified as nitrite with Griess reagent. There is a good correlation between the biological generation of NO determined by fluorescence microscopy and with Griess reagent. Some of the synthesized compounds exhibited both nitric oxide and reactive oxygen species generation abilities and represent potential NO donors in plant tissues.

Indexed as

AldehydesArabidopsisEthylenediaminesFluoresceinsFluorescent DyesMicroscopy, FluorescenceNitric OxideNitric Oxide DonorsNitritesOxadiazolesPlant LeavesReactive Oxygen SpeciesSchiff BasesSeedlingsSeedsStereoisomerism2',7'-dichlorodihydrofluorescein diacetateAldehydesEthylenediaminesFluoresceinsFluorescent DyesfuroxansGriess reagentNitric OxideNitric Oxide DonorsNitritesOxadiazolesReactive Oxygen SpeciesSchiff BasesSulfanilamides

Identifiers

PMID29990316
PMCPMC6038987
OpenAlexW2841847646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.