Evidence map›Paper›PMID 29989926›Full record

ArticleIEEE transactions on bio-medical engineering2018

Learning Based Segmentation of CT Brain Images: Application to Postoperative Hydrocephalic Scans.

Venkateswararao Cherukuri, Peter Ssenyonga, Benjamin C Warf, Abhaya V Kulkarni, Vishal Monga, Steven J Schiff

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  7. Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023
    Article
  8. Deep learning in precision medicine and focus on glioma.Bioengineering & translational medicine · 2023
    Review
  9. Article
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  11. Review
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  16. Machine learning predicts risk of cerebrospinal fluid shunt failure in children: a study from the hydrocephalus clinical research network.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Venkateswararao Cherukuri
Peter Ssenyonga
Benjamin C Warf
Abhaya V Kulkarni
Vishal Monga
Steven J Schiff

Funding

Neurocognitive outcomes and changes in brain and CSF volume after treatment of post-infectious hydrocephalus in Ugandan infants by shunting or ETV/CPC: a randomized prospective trialR01HD085853 · NICHD · YALE UNIVERSITY · PI KULKARNI, ABHAYA V, SCHIFF, STEVEN JOHN · 2015 to 2025
$4.7M
Improving infant hydrocephalus outcomes in Uganda: Predicting developmental outcomes and identifying patients at risk for early treatment failure after ETV/CPCR01HD096693 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI LIN, PEI-YI, WARF, BENJAMIN CURTIS · 2018 to 2022
$2.8M
NICHD NIH HHS R01 HD085853NICHD NIH HHS R01 HD096693
6 · The paper itself

Abstract

objectiveHydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF [before and after surgery, i.e., preoperative (pre-op) versus postoperative (post-op)] plays a crucial role in evaluating surgical treatment. Segmentation of pre-op images is often a relatively straightforward problem and has been well researched. However, segmenting post-op computational tomographic (CT) scans becomes more challenging due to distorted anatomy and subdural hematoma collections pressing on the brain. Most intensity- and feature-based segmentation methods fail to separate subdurals from brain and CSF as subdural geometry varies greatly across different patients and their intensity varies with time. We combat this problem by a learning approach that treats segmentation as supervised classification at the pixel level, i.e., a training set of CT scans with labeled pixel identities is employed.

methodsOur contributions include: 1) a dictionary learning framework that learns class (segment) specific dictionaries that can efficiently represent test samples from the same class while poorly represent corresponding samples from other classes; 2) quantification of associated computation and memory footprint; and 3) a customized training and test procedure for segmenting post-op hydrocephalic CT images.

resultsExperiments performed on infant CT brain images acquired from the CURE Children's Hospital of Uganda reveal the success of our method against the state-of-the-art alternatives. We also demonstrate that the proposed algorithm is computationally less burdensome and exhibits a graceful degradation against a number of training samples, enhancing its deployment potential.

Indexed as

AlgorithmsBrainHumansHydrocephalusImage Interpretation, Computer-AssistedInfantMachine LearningTomography, X-Ray Computed

Identifiers

PMID29989926
PMCPMC6062853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.