Evidence map›Paper›PMID 29989842›Full record

ArticleExpert opinion on therapeutic targets2018

How little is known about the role of human FOXP3+ Tregs in tumors.

Tatiana Akimova, Wayne W Hancock

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Expert opinion on therapeutic targets, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tatiana Akimovaa Pathology and Laboratory Medicine, Perelman School of Medicine , University of Pennsylvania , Philadelphia , PA , USA.
Wayne W Hancocka Pathology and Laboratory Medicine, Perelman School of Medicine , University of Pennsylvania , Philadelphia , PA , USA.
University of Pennsylvania · US

Funding

Class IIa HDAC and MEF2 Targeting to Promote Foxp3+ Treg Cell FunctionsR01AI123241 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2016 to 2020
$2.1M
INHIBITION OF A TREG DEUBIQUITINASE, USP7, PROMOTES ANTI-TUMOR IMMUNITYR01CA177852 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2015 to 2019
$2.1M
NCI NIH HHS R01 CA177852NIAID NIH HHS R01 AI123241
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsForkhead Transcription FactorsHumansNeoplasmsSpecies SpecificityT-Lymphocytes, RegulatoryForkhead Transcription FactorsFOXP3 protein, humanclinical oncologyclinical researchimmuno-oncologyimmunotherapyT-regulatory cells

Identifiers

PMID29989842
PMCPMC6294964
OpenAlexW2880663997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.