ArticleeLife2018
Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 51 citations in OpenAlex.
- A review of the immunogenetics of Stevens-Johnson syndrome and toxic epidermal necrolysis.Global medical genetics · 2025Review
- Effects of Calreticulin Mutations on HLA Class I Expression in Myeloproliferative Neoplasms.bioRxiv : the preprint server for biology · 2025Article
- HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design.NPJ vaccines · 2025Article
- CD8Nature communications · 2024Article
- Gemcitabine Modulates HLA-I Regulation to Improve Tumor Antigen Presentation by Pancreatic Cancer Cells.International journal of molecular sciences · 2024Article
- Mass Spectrometric Profiling of HLA-B44 Peptidomes Provides Evidence for Tapasin-Mediated Tryptophan Editing.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Major histocompatibility complex class I assembly within endolysosomal pathways.Current opinion in immunology · 2023Review
- Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.Science immunology · 2023Article
- Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for tapasin-mediated tryptophan editing.bioRxiv : the preprint server for biology · 2023Article
- Downregulation of LRP/LR with siRNA inhibits several cancer hallmarks in lung cancer cells.FEBS open bio · 2023Article
- Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes.eLife · 2023Article
- SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D.Cell reports · 2022Article
- Technical and clinical aspects of the histocompatibility crossmatch assay in solid organ transplantationBiomedica : revista del Instituto Nacional de Salud · 2022Article
- Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence.Biomedicines · 2022Review
- Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex.Scientific reports · 2022Article
- Immune escape pathways from the HBV coreFrontiers in immunology · 2022Article
- Allotype-Specific Glycosylation and Cellular Localization of Human Leukocyte Antigen Class I Proteins.Journal of proteome research · 2021Article
- Conformational sensing of major histocompatibility complex (MHC) class I molecules by immune receptors and intracellular assembly factors.Current opinion in immunology · 2021Review
- Biomarker Discovery in Patients with Immunotherapy-Treated Melanoma with Imaging Mass Cytometry.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021Article
- Conserved epitopes with high HLA-I population coverage are targets of CD8Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Brogan Yarzabek *Department of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0002-9632-096X
Anita J Zaitouna *Department of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0001-5513-6886
Eli Olson *Department of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0003-2319-7144
Gayathri N SilvaDepartment of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0002-2687-2144
Jie GengDepartment of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0001-8722-2228
Aviva GeretzUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, United States.
Rasmi ThomasUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, United States.ORCID 0000-0002-2116-2418
Sujatha KrishnakumarSirona Genomics, Immucor, Inc, California, United States.ORCID 0000-0003-1961-3432
Daniel S RamonDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Arizona, United States.ORCID 0000-0002-3067-5653
Malini RaghavanDepartment of Microbiology and Immunology, Michigan Medicine, University of Michigan, Michigan, United States.ORCID 0000-0002-1345-9318
Michigan United · USHenry M. Jackson Foundation · USImmucor (United States) · USMayo Clinic Hospital · US
Funding
RESEARCH TRAINING IN EXPERIMENTAL IMMUNOPATHOLOGYT32AI007413 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bethany B. Moore · 1993 to 2026
$9.8MINTERACTIONS &MECHANISMS OF FUNCTION OF THE TAP COMPLEXR01AI044115 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MALINI RAGHAVAN · 1999 to 2026
$9.3MMolecular Mechanisms of Microbial Pathogenesis Training ProgramT32AI007528 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 1998 to 2024
$6.8MCellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6MPeptide Repertoires of HLA class I moleculesR21AI126054 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAGHAVAN, MALINI · 2017 to 2018
$428kInteractions and mechanisms of function of the TAP ComplexR56AI044115 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAGHAVAN, MALINI · 2008 to 2008
$386kNIAID NIH HHS R01 AI044115NIAID NIH HHS R21 AI126054NIAID NIH HHS R56 AI044115NIAID NIH HHS T32 AI007413NIAID NIH HHS T32 AI007528NIGMS NIH HHS T32 GM145304NIH HHS AI044115NIH HHS R21AI126054NIH HHS T32AI007528
Abstract
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8
Indexed as
Antigen PresentationGenetic VariationAntibodies, MonoclonalCD8-Positive T-LymphocytesGene Expression RegulationHalf-LifeHLA-B AntigensHumansPeptide FragmentsAntibodies, MonoclonalHLA-B AntigensPeptide Fragmentsexpressionhalf-lifeHLA-BhumanimmunologyinflammationMHC class Ipeptidometransporter associated with antigen processing
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.