ReviewJournal of current ophthalmology2018
Updates on Managements for Keratoconus.
Review in Journal of current ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Early Detection of Keratoconus: Diagnostic Advances and Their Impact on Visual Outcomes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Efficacy of implantable Collamer lens after corneal cross-linking in patients with keratoconus: a systematic review and meta-analysis.International ophthalmology · 2025Pooled it
- The candidate proteins associated with keratoconus: A meta-analysis and bioinformatic analysis.PloS one · 2024Pooled it
- The effects of green tea tablets and metformin on ovulation and menstrual cycle regularity in women with polycystic ovary syndrome.Journal of medicine and life · 2024Trial
- Biomechanical assessments of high-fluence corneal cross-linking with supplemental oxygen using optical coherence elastography inJournal of biomedical optics · 2026Article
- In Vitro Assessment of Nintedanib in Keratoconus Corneal Stromal Microenvironment.Biomolecules · 2026Article
- Clinical Outcomes and Complications After INTACS Implantation in Keratoconus: A Systematic Review.Journal of clinical medicine · 2026Review
- Role of toric intraocular lenses in the correction of keratoconic eyes with cataract.Journal of cataract and refractive surgery · 2026Article
- Omics in Keratoconus: From Molecular to Clinical Practice.Journal of clinical medicine · 2025Review
- Strategies for Early Keratoconus Diagnosis: A Narrative Review of Evaluating Affordable and Effective Detection Techniques.Journal of clinical medicine · 2025Review
- Quality of Life in Keratoconus Patients; A Comparison Between Spectacle, Rigid Gas-Permeable Lens, and Corneal Stromal Ring Segment Implantation.Beyoglu eye journal · 2025Article
- Corneal surface changes after stromal lenticule addition keratoplasty combined with cross-linking for severe keratoconus.International journal of ophthalmology · 2025Article
- Simultaneous versus sequential corneal cross-linking and intracorneal ring segments implantation for keratoconus: two-year study.International journal of ophthalmology · 2025Article
- Experiences of keratoconus patients attending public eye care facilities in South Africa.African journal of primary health care & family medicine · 2024Article
- Headache Attributed to Refractive Error: Improvement after Topography-Guided Photorefractive Keratectomy with Corneal Cross-Linking in Patients with Keratoconus.Journal of clinical medicine · 2024Article
- Keratoconus: imaging modalities and management.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Review
- Distinguishing subclinical from clinical keratoconus by corneal measurements.Frontiers in medicine · 2024Article
- Article
- Ethnicity, Progressive Keratoconus, and Outcomes after Corneal Cross-Linking in Southern Israel.Life (Basel, Switzerland) · 2023Article
- Analysis of the diagnostic accuracy of Belin/Ambrósio Enhanced Ectasia and Corvis ST parameters for subclinical keratoconus.International ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeKeratoconus is a progressive disease of the cornea which can lead to blindness as irregular astigmatism increases. Currently, a variety of methods are available for the treatment of keratoconus, and in certain cases, it may be difficult to choose the most appropriate option. This article reviews available treatment modalities for keratoconus to provide the practitioner with practical and useful information for selecting the most suitable option for each individual patient.
methodsTo review treatment methods for different stages of keratoconus, PubMed (United States National Library of Medicine) and Scopus (Elsevier BV) databases were searched using the keywords "keratoconus", "contact lens", "cross-linking", "Intacs", "keratoplasty", "gene therapy", and "irregular astigmatism", and related articles were reviewed based on disease assessment parameters and treatment methods.
resultsVarious methods are available for the treatment of keratoconus: eyeglasses and contact lenses in the early stages, cross-linking for stabilizing disease progression, intrastromal corneal ring segments (ICRS) for reducing refractive errors or flattening the cornea, and penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK), conductive keratoplasty, gene therapy and more recently, bowman layer transplantation (BL transplantation) in advanced stages of the disease. To achieve optimum results, it is essential to choose the best option for each individual patient.
conclusionsA commonality of the reviewed papers was the advancement of novel diagnostic and treatment methods in ophthalmology, which can delay the need for corneal grafting. A better understanding of keratoconus treatment options can help enhance visual rehabilitation and prevent blindness in keratoconus patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.